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ICD-10 Coding for Acute Leukemia(C91.0, C92.0)

Complete ICD-10-CM coding and documentation guide for Acute Leukemia. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

Acute Lymphoblastic LeukemiaAcute Myeloblastic Leukemia

Related ICD-10 Code Ranges

Complete code families applicable to Acute Leukemia

C91-C95Primary Range

Leukemia

This range includes all types of leukemia, with specific codes for acute forms.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
C91.0Acute lymphoblastic leukemia [ALL]Use for confirmed cases of ALL with specified lineage.
  • ≥20% lymphoblasts in marrow
  • Flow cytometry confirming B/T-cell lineage
C92.0Acute myeloblastic leukemia [AML]Use for confirmed cases of AML with specified genetic markers.
  • Auer rods on smear
  • MPO+ staining
  • NPM1 or CEBPA mutation

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for acute leukemia

Essential facts and insights about Acute Leukemia

The ICD-10 code for acute lymphoblastic leukemia is C91.0, and for acute myeloblastic leukemia, it is C92.0.

Primary ICD-10-CM Codes for acute leukemia

Acute lymphoblastic leukemia [ALL]
Non-billable Code

Decision Criteria

clinical Criteria

  • Presence of ≥20% lymphoblasts in marrow.

Applicable To

  • T-cell precursor leukemia
  • B-cell precursor leukemia

Excludes

  • Chronic lymphocytic leukemia (C91.1-)

Clinical Validation Requirements

  • ≥20% lymphoblasts in marrow
  • Flow cytometry confirming B/T-cell lineage

Code-Specific Risks

  • Misclassification if lineage is not specified.

Coding Notes

  • Ensure lineage and remission status are documented.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Pancytopenia

D61.818
Use if pancytopenia is present with leukemia.

Disseminated intravascular coagulation (DIC)

D65
Use if DIC is present with APL.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Acute myeloblastic leukemia [AML]

C92.0
AML is confirmed by myeloblasts and specific genetic markers.

Acute lymphoblastic leukemia [ALL]

C91.0
ALL is confirmed by lymphoblasts and specific lineage markers.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Acute Leukemia to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code C91.0.

Impact

Clinical: Inaccurate treatment planning., Regulatory: Potential audit issues., Financial: Incorrect DRG assignment.

Mitigation Strategy

Ensure genetic testing is documented., Include results in patient records.

Impact

Reimbursement: Incorrect DRG assignment leading to reduced reimbursement., Compliance: Non-compliance with coding guidelines., Data Quality: Inaccurate clinical data representation.

Mitigation Strategy

Use C91.0- or C92.0- for active disease.

Impact

Using remission codes without proper documentation.

Mitigation Strategy

Ensure remission status is clearly documented in the medical record.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Acute Leukemia, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Acute Leukemia

Use these documentation templates to ensure complete and accurate documentation for Acute Leukemia. These templates include all required elements for proper coding and billing.

New diagnosis of ALL

Specialty: Hematology

Required Elements

  • Lineage specification
  • Remission status
  • Blast percentage
  • Flow cytometry results

Example Documentation

B-cell ALL confirmed by flow cytometry (CD19+, CD22+). Bone marrow shows 30% lymphoblasts.

Examples: Poor vs. Good Documentation

Poor Documentation Example
Acute leukemia
Good Documentation Example
B-cell ALL with 25% lymphoblasts, FLT3-negative, not in remission.
Explanation
The good example specifies lineage, blast percentage, and remission status, allowing for accurate coding.

Need help with ICD-10 coding for Acute Leukemia? Ask your questions below.

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