Back to HomeBeta

ICD-10 Coding for Amyloidosis(E85.81, E85.82)

Complete ICD-10-CM coding and documentation guide for Amyloidosis. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

Amyloid diseaseAmyloid protein deposition

Related ICD-10 Code Ranges

Complete code families applicable to Amyloidosis

E85Primary Range

Amyloidosis

This range includes all types of amyloidosis, which are characterized by abnormal protein deposits in tissues and organs.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
E85.81AL amyloidosisUse when AL amyloidosis is confirmed with organ involvement.
  • Light chain amyloid confirmed by serum FLC ratio >6.0 and bone marrow plasmacytosis ≥10%
E85.82Hereditary ATTR amyloidosisUse for confirmed ATTR amyloidosis with genetic testing.
  • Grade 2-3 myocardial uptake on 99mTc-PYP SPECT with H/CL ratio >1.5

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for AL amyloidosis

Essential facts and insights about Amyloidosis

The ICD-10 code for AL amyloidosis is E85.81, used when light chain amyloidosis is confirmed with organ involvement.

Primary ICD-10-CM Codes for amyloidosis

AL amyloidosis
Billable Code

Decision Criteria

clinical Criteria

  • Confirmed AL amyloidosis with organ involvement.

Applicable To

  • Primary systemic amyloidosis

Excludes

  • Secondary systemic amyloidosis (E85.89)

Clinical Validation Requirements

  • Light chain amyloid confirmed by serum FLC ratio >6.0 and bone marrow plasmacytosis ≥10%

Code-Specific Risks

  • Risk of incorrect coding if organ involvement is not specified.

Coding Notes

  • Ensure organ involvement is documented to support coding.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Cardiomyopathy in amyloidosis

I43
Use to specify cardiac involvement in amyloidosis.

Other hereditary and idiopathic neuropathies

G60.8
Use to specify neuropathy involvement in amyloidosis.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Hereditary ATTR amyloidosis

E85.82
Use E85.82 for confirmed ATTR amyloidosis with genetic testing.

AL amyloidosis

E85.81
Use E85.81 for confirmed AL amyloidosis with light chain involvement.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Amyloidosis to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code E85.81.

Impact

Clinical: Inadequate treatment planning., Regulatory: Non-compliance with documentation standards., Financial: Potential claim denials.

Mitigation Strategy

Use templates to ensure all elements are documented., Regular training on documentation standards.

Impact

Reimbursement: Incorrect coding can lead to claim denials., Compliance: Non-compliance with coding guidelines., Data Quality: Poor data quality affecting patient records.

Mitigation Strategy

Always specify the subtype of amyloidosis when known.

Impact

Audits may target incorrect use of unspecified codes when specific types are documented.

Mitigation Strategy

Ensure all documentation specifies the type and organ involvement.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Amyloidosis, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Amyloidosis

Use these documentation templates to ensure complete and accurate documentation for Amyloidosis. These templates include all required elements for proper coding and billing.

Cardiac amyloidosis with ATTR

Specialty: Cardiology

Required Elements

  • Type of amyloidosis
  • Diagnostic confirmation
  • Organ involvement

Example Documentation

Amyloidosis Status: Type: ATTR, Diagnostic confirmation: SPECT H/CL ratio 1.8, Organ involvement: Cardiac.

Examples: Poor vs. Good Documentation

Poor Documentation Example
Cardiac amyloidosis suspected.
Good Documentation Example
Grade 2 diffuse myocardial uptake on 99mTc-DPD SPECT (H/CL ratio 1.8) with negative serum immunofixation, consistent with wild-type ATTR amyloidosis.
Explanation
The good example provides specific diagnostic criteria and test results supporting the diagnosis.

Need help with ICD-10 coding for Amyloidosis? Ask your questions below.

Ask about any ICD-10 CM code, or paste a medical note

We build tools for
clinician happiness.

Learn More at Freed.ai
Back to HomeBeta

Built by Freed

Try Freed for free for 7 days.

Learn more