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ICD-10 Coding for B-cell Acute Lymphoblastic Leukemia(C91.00, C91.01, C91.02)

Complete ICD-10-CM coding and documentation guide for B-cell Acute Lymphoblastic Leukemia. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

B-ALLB-cell ALLBrother Cell Acute Lymphoblastic Leukemia

Related ICD-10 Code Ranges

Complete code families applicable to B-cell Acute Lymphoblastic Leukemia

C91.0-C91.02Primary Range

Acute lymphoblastic leukemia

This range covers all stages and statuses of B-cell acute lymphoblastic leukemia, including active disease, remission, and relapse.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
C91.00Acute lymphoblastic leukemia, not having achieved remissionUse when B-ALL is newly diagnosed or when remission status is not achieved.
  • Bone marrow biopsy showing ≥20% blasts
  • Immunophenotyping confirming B-cell markers (e.g., CD19, CD79a)
C91.01Acute lymphoblastic leukemia, in remissionUse when B-ALL is in remission, confirmed by clinical tests.
  • Flow cytometry showing ≤5% blasts
  • Documentation of remission status
C91.02Acute lymphoblastic leukemia, in relapseUse when B-ALL has relapsed after achieving remission.
  • Bone marrow biopsy showing ≥20% blasts post-treatment
  • Clinical documentation of relapse

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for B-cell acute lymphoblastic leukemia

Essential facts and insights about B-cell Acute Lymphoblastic Leukemia

The ICD-10 code for B-cell acute lymphoblastic leukemia varies by status: C91.00 for active disease, C91.01 for remission, and C91.02 for relapse.

Primary ICD-10-CM Codes for brother cell acute lymphoblastic leukemia

Acute lymphoblastic leukemia, not having achieved remission
Billable Code

Decision Criteria

clinical Criteria

  • Presence of ≥20% blasts in bone marrow biopsy

Applicable To

  • New diagnosis of B-ALL
  • Persistent disease without remission

Excludes

  • T-cell acute lymphoblastic leukemia (C91.10)

Clinical Validation Requirements

  • Bone marrow biopsy showing ≥20% blasts
  • Immunophenotyping confirming B-cell markers (e.g., CD19, CD79a)

Code-Specific Risks

  • Misclassification if remission status is not clearly documented.

Coding Notes

  • Ensure documentation specifies B-cell lineage to avoid confusion with T-cell ALL.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Encounter for antineoplastic immunotherapy

Z51.12
Use when the patient is receiving immunotherapy treatments such as CAR-T.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Acute lymphoblastic leukemia of T-cell type

C91.10
Presence of T-cell markers such as CD3 and CD7.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting B-cell Acute Lymphoblastic Leukemia to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code C91.00.

Impact

Clinical: Inaccurate treatment planning and monitoring., Regulatory: Potential non-compliance with coding standards., Financial: Risk of claim denials or incorrect reimbursement.

Mitigation Strategy

Ensure remission status is clearly documented in medical records., Regularly update patient status in clinical notes.

Impact

Reimbursement: Incorrect coding may lead to denied claims or reduced reimbursement., Compliance: Non-compliance with ICD-10 coding guidelines., Data Quality: Inaccurate data reporting and clinical records.

Mitigation Strategy

Use C91.00, C91.01, or C91.02 based on the clinical status of B-ALL.

Impact

Coding remission status inaccurately can lead to audit discrepancies.

Mitigation Strategy

Implement regular training for coders on remission status documentation.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for B-cell Acute Lymphoblastic Leukemia, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for B-cell Acute Lymphoblastic Leukemia

Use these documentation templates to ensure complete and accurate documentation for B-cell Acute Lymphoblastic Leukemia. These templates include all required elements for proper coding and billing.

B-ALL Diagnosis and Treatment

Specialty: Oncology

Required Elements

  • Bone marrow biopsy results
  • Immunophenotyping details
  • Cytogenetic findings
  • Remission or relapse status

Example Documentation

Patient diagnosed with B-ALL: Bone marrow biopsy shows 40% CD19+/CD79a+ blasts. Cytogenetics reveal t(9;22). Diagnosis: B-ALL in relapse (C91.02).

Examples: Poor vs. Good Documentation

Poor Documentation Example
Patient with B-ALL receiving chemotherapy.
Good Documentation Example
45M with B-ALL (C91.02): Bone marrow: 30% CD19+/CD79a+/CD10+ blasts; FISH positive for BCR-ABL1 p190. CNS involvement: 5 WBCs with blasts in CSF. Current phase: Relapse post-blina + CAR-T therapy (Z51.12).
Explanation
The good example provides detailed clinical findings and treatment specifics, supporting accurate coding.

Need help with ICD-10 coding for B-cell Acute Lymphoblastic Leukemia? Ask your questions below.

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