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ICD-10 Coding for Diffuse Large B-Cell Lymphoma(C83.3, C83.39)

Complete ICD-10-CM coding and documentation guide for Diffuse Large B-Cell Lymphoma. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

DLBCLB-cell lymphomaDiffuse Large Cell LymphomaLarge Cell LymphomaNon-Hodgkin Lymphoma, Diffuse Large B-Cell Typediffuse bcell lymphomadiffuse largecell lymphoma

Related ICD-10 Code Ranges

Complete code families applicable to Diffuse Large B-Cell Lymphoma

C83.3-C83.39Primary Range

Diffuse large B-cell lymphoma codes

This range covers the primary codes for diffuse large B-cell lymphoma, including site-specific and remission codes.

Personal history of non-Hodgkin lymphoma

Used when the lymphoma is in remission and no longer active.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
C83.3Diffuse large B-cell lymphomaUse for confirmed cases of DLBCL with specified site.
  • Biopsy-confirmed DLBCL
  • Immunophenotyping showing CD20+
C83.39Diffuse large B-cell lymphoma, extranodal and solid organ sitesUse when DLBCL is confirmed in extranodal sites.
  • Imaging or biopsy confirmation of organ involvement

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for diffuse large B-cell lymphoma

Essential facts and insights about Diffuse Large B-Cell Lymphoma

The ICD-10 code for diffuse large B-cell lymphoma is C83.3, with specific codes for extranodal sites like C83.39.

Primary ICD-10-CM Codes for brother cell lymphoma

Diffuse large B-cell lymphoma
Non-billable Code

Decision Criteria

clinical Criteria

  • Biopsy-confirmed DLBCL with specific immunophenotyping

Applicable To

  • DLBCL of lymph nodes

Excludes

  • Burkitt lymphoma (C83.7)
  • Anaplastic large cell lymphoma (C84.6)

Clinical Validation Requirements

  • Biopsy-confirmed DLBCL
  • Immunophenotyping showing CD20+

Code-Specific Risks

  • Confusion with other lymphomas if site not specified

Coding Notes

  • Ensure site is specified to avoid miscoding.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Personal history of non-Hodgkin lymphoma

Z85.81
Use when lymphoma is in remission and no active treatment is ongoing.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Burkitt lymphoma

C83.7
MYC+ with IG partner on FISH

ALK- anaplastic large cell lymphoma

C84.7
CD30+ but ALK-

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Diffuse Large B-Cell Lymphoma to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code C83.3.

Impact

Clinical: Impacts treatment decisions., Regulatory: Non-compliance with coding standards., Financial: Potential for incorrect billing.

Mitigation Strategy

Review pathology reports for site details, Educate staff on documentation standards

Impact

Reimbursement: Incorrect DRG assignment leading to reimbursement issues., Compliance: Non-compliance with coding guidelines., Data Quality: Inaccurate clinical data representation.

Mitigation Strategy

Use C83.39 for extranodal involvement instead of secondary site codes.

Impact

Lack of site documentation can lead to audit findings.

Mitigation Strategy

Ensure all documentation includes specific site details.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Diffuse Large B-Cell Lymphoma, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Diffuse Large B-Cell Lymphoma

Use these documentation templates to ensure complete and accurate documentation for Diffuse Large B-Cell Lymphoma. These templates include all required elements for proper coding and billing.

Oncology Progress Note

Specialty: Oncology

Required Elements

  • Subjective symptoms
  • Objective findings
  • Assessment
  • Plan

Example Documentation

**Subjective**: Night sweats, 10% weight loss over 6 weeks. **Objective**: PET/CT: SUVmax 18.2 in mesenteric nodes **Labs**: LDH 620 U/L, Hb 9.8 g/dL **Biopsy**: Diffuse large B-cells (CD20+, BCL2+, Ki-67 90%) **Assessment**: DLBCL, lymph nodes of abdomen (C83.33) with B-symptoms **Plan**: R-CHOP initiated 3/24/25

Examples: Poor vs. Good Documentation

Poor Documentation Example
Lymphoma in abdomen.
Good Documentation Example
Biopsy-confirmed DLBCL of abdominal lymph nodes (CD20+, BCL6+, MYC 40% by IHC).
Explanation
The good example specifies the type of lymphoma and includes immunophenotyping results.

Need help with ICD-10 coding for Diffuse Large B-Cell Lymphoma? Ask your questions below.

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