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ICD-10 Coding for Cancer Antigen 125(R97.1, C56.9)

Complete ICD-10-CM coding and documentation guide for Cancer Antigen 125. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

CA-125Carbohydrate Antigen 125

Related ICD-10 Code Ranges

Complete code families applicable to Cancer Antigen 125

R97-R99Primary Range

Abnormal findings on examination of blood, without diagnosis

This range includes codes for abnormal tumor markers, including elevated CA-125.

Malignant neoplasms of ovary and other uterine adnexa

Relevant for coding ovarian cancer, which is monitored using CA-125 levels.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
R97.1Elevated cancer antigen 125 [CA 125]Use when CA-125 is elevated and not directly linked to a confirmed malignancy.
  • CA-125 level ≥35 U/mL
  • Clinical context indicating monitoring or diagnosis of a condition
C56.9Malignant neoplasm of ovary, unspecifiedUse as a primary code when CA-125 is used for monitoring ovarian cancer.
  • Histological confirmation of ovarian cancer

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for elevated CA-125

Essential facts and insights about Cancer Antigen 125

The ICD-10 code for elevated CA-125 is R97.1, used when CA-125 levels are elevated without a confirmed malignancy.

Primary ICD-10-CM Codes for cancer antigen 125

Elevated cancer antigen 125 [CA 125]
Billable Code

Decision Criteria

clinical Criteria

  • Patient has elevated CA-125 with no confirmed malignancy.

coding Criteria

  • Do not use R97.1 as a primary code for cancer monitoring.

Applicable To

  • Elevated CA-125 without confirmed cancer

Excludes

  • CA-125 used for screening purposes

Clinical Validation Requirements

  • CA-125 level ≥35 U/mL
  • Clinical context indicating monitoring or diagnosis of a condition

Code-Specific Risks

  • Misuse as a primary code for cancer monitoring

Coding Notes

  • Ensure documentation specifies the clinical context and CA-125 levels.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Follow-up examination after treatment for malignant neoplasm

Z08
Use alongside R97.1 for surveillance post-cancer treatment.

Elevated cancer antigen 125 [CA 125]

R97.1
Use to indicate elevated CA-125 levels in ovarian cancer monitoring.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Malignant neoplasm of ovary, unspecified

C56.9
Use C56.9 when CA-125 is used for monitoring known ovarian cancer.

Benign neoplasm of ovary

D27
Use D27 for benign ovarian tumors, not C56.9.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Cancer Antigen 125 to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code R97.1.

Impact

Clinical: May lead to misinterpretation of test results., Regulatory: Non-compliance with documentation standards., Financial: Potential claim denials due to lack of justification.

Mitigation Strategy

Always include clinical indication in the patient's record., Use templates to ensure completeness.

Impact

Reimbursement: Incorrect sequencing can lead to claim denials., Compliance: Non-compliance with coding guidelines., Data Quality: Affects accuracy of cancer registry data.

Mitigation Strategy

Always sequence the malignancy code first, followed by R97.1.

Impact

R97.1 used as primary code for cancer monitoring.

Mitigation Strategy

Educate coders on proper sequencing rules.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Cancer Antigen 125, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Cancer Antigen 125

Use these documentation templates to ensure complete and accurate documentation for Cancer Antigen 125. These templates include all required elements for proper coding and billing.

Routine monitoring of ovarian cancer

Specialty: Oncology

Required Elements

  • Patient history of ovarian cancer
  • Current CA-125 levels
  • Clinical context for testing

Example Documentation

Patient with history of stage IIIC ovarian cancer presents for routine CA-125 monitoring. Current CA-125: 85 U/mL (Ref: <35).

Examples: Poor vs. Good Documentation

Poor Documentation Example
CA-125 elevated.
Good Documentation Example
CA-125 elevated to 85 U/mL in patient with history of ovarian cancer.
Explanation
The good example provides specific CA-125 levels and clinical context.

Need help with ICD-10 coding for Cancer Antigen 125? Ask your questions below.

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