Back to HomeBeta

ICD-10 Coding for Central Nervous System Lymphoma(C83.390, C83.3, C79.31)

Complete ICD-10-CM coding and documentation guide for Central Nervous System Lymphoma. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

CNS LymphomaPrimary CNS LymphomaSecondary CNS Lymphoma

Related ICD-10 Code Ranges

Complete code families applicable to Central Nervous System Lymphoma

C83.3-C83.39Primary Range

Diffuse large B-cell lymphoma

This range includes codes for diffuse large B-cell lymphoma, which is the most common type of CNS lymphoma.

Secondary malignant neoplasm of brain

Used for coding secondary CNS lymphoma when there is systemic involvement.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
C83.390Primary central nervous system lymphomaUse when documentation specifies 'primary CNS lymphoma' with no systemic disease.
  • Biopsy confirming DLBCL in brain/spinal cord
  • Negative PET/CT for systemic involvement
C83.3Diffuse large B-cell lymphomaUse when CNS lymphoma is documented without 'primary' and no systemic disease is evident.
  • Biopsy confirming DLBCL
  • Absence of 'primary' designation in documentation
C79.31Secondary malignant neoplasm of brainUse when CNS involvement is secondary to a systemic lymphoma.
  • Documentation of systemic origin
  • Evidence of CNS involvement secondary to systemic disease

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for primary CNS lymphoma

Essential facts and insights about Central Nervous System Lymphoma

The ICD-10 code for primary central nervous system lymphoma is C83.390, effective from October 2025.

Primary ICD-10-CM Codes for central nervous system lymphoma

Primary central nervous system lymphoma
Billable Code

Decision Criteria

documentation Criteria

  • Documentation must specify 'primary CNS lymphoma'.

Applicable To

  • Primary CNS diffuse large B-cell lymphoma

Excludes

  • Secondary CNS lymphoma (C79.31)

Clinical Validation Requirements

  • Biopsy confirming DLBCL in brain/spinal cord
  • Negative PET/CT for systemic involvement

Code-Specific Risks

  • Misclassification if 'primary' is not documented.

Coding Notes

  • Ensure 'primary' is documented to use this code.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Other specified disorders of brain

G93.89
Use for associated cerebral edema.

Altered mental status, unspecified

R41.82
Use for associated symptoms.

Personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissue

Z85.79
Use if treatment has ceased and history is relevant.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Secondary malignant neoplasm of brain

C79.31
Use when CNS involvement is secondary to systemic lymphoma.

Primary central nervous system lymphoma

C83.390
Requires 'primary' designation in documentation.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Central Nervous System Lymphoma to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code C83.390.

Impact

Clinical: May lead to inappropriate treatment planning., Regulatory: Non-compliance with coding standards., Financial: Potential for claim denial or reduced reimbursement.

Mitigation Strategy

Educate clinicians on documentation requirements., Implement checklist for lymphoma diagnosis.

Impact

Reimbursement: May lead to incorrect DRG assignment., Compliance: Non-compliance with coding guidelines., Data Quality: Inaccurate clinical data representation.

Mitigation Strategy

Ensure documentation specifies 'primary CNS lymphoma'.

Impact

Reimbursement: Incorrect billing and potential claim denial., Compliance: Violation of coding rules., Data Quality: Misleading data on cancer spread.

Mitigation Strategy

Do not add C79.3 when using C83.3.

Impact

Misclassification of CNS lymphoma as primary or secondary.

Mitigation Strategy

Ensure thorough documentation and use of decision criteria.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Central Nervous System Lymphoma, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Central Nervous System Lymphoma

Use these documentation templates to ensure complete and accurate documentation for Central Nervous System Lymphoma. These templates include all required elements for proper coding and billing.

Primary CNS Lymphoma Diagnosis

Specialty: Neurology

Required Elements

  • Biopsy results
  • Imaging findings
  • Systemic disease exclusion

Example Documentation

65M with cognitive decline. MRI shows enhancing lesions. Biopsy confirms CD20+ DLBCL. PET/CT negative for systemic disease. Diagnosis: Primary CNS lymphoma (C83.390).

Examples: Poor vs. Good Documentation

Poor Documentation Example
Lymphoma in brain.
Good Documentation Example
Primary CNS diffuse large B-cell lymphoma involving left frontal lobe, confirmed via CT-guided biopsy (M9680/3). No systemic involvement on FDG-PET.
Explanation
The good example specifies 'primary', includes biopsy confirmation, and rules out systemic involvement.

Need help with ICD-10 coding for Central Nervous System Lymphoma? Ask your questions below.

Ask about any ICD-10 CM code, or paste a medical note

We build tools for
clinician happiness.

Learn More at Freed.ai
Back to HomeBeta

Built by Freed

Try Freed for free for 7 days.

Learn more