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ICD-10 Coding for Clotting Disorder(D68.51, D68.59, D68.32)

Complete ICD-10-CM coding and documentation guide for Clotting Disorder. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

Coagulation DefectThrombophiliaHypercoagulable State

Related ICD-10 Code Ranges

Complete code families applicable to Clotting Disorder

D68.0-D68.9Primary Range

Coagulation Defects

This range includes various coagulation defects such as Von Willebrand disease, hereditary factor deficiencies, and thrombophilia.

Embolism and Thrombosis

This range is relevant for coding active thrombosis, which often coexists with clotting disorders.

Long-term (current) drug therapy

This range includes codes for long-term anticoagulant use, which is common in patients with clotting disorders.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
D68.51Activated protein C resistanceUse when genetic testing confirms Factor V Leiden mutation.
  • Factor V Leiden PCR positive
  • APC resistance ratio <2.0
D68.59Other primary thrombophiliaUse for inherited thrombophilias other than Factor V Leiden.
  • Genetic confirmation of thrombophilia
D68.32Hemorrhagic disorder due to extrinsic circulating anticoagulantsUse when bleeding is directly linked to anticoagulant use.
  • Documented bleeding with therapeutic anticoagulant use

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for Factor V Leiden

Essential facts and insights about Clotting Disorder

The ICD-10 code for Factor V Leiden is D68.51, used for activated protein C resistance confirmed by genetic testing.

Primary ICD-10-CM Codes for clotting disorder

Activated protein C resistance
Billable Code

Decision Criteria

clinical Criteria

  • Confirmed Factor V Leiden mutation via PCR

Applicable To

  • Factor V Leiden

Excludes

  • Antiphospholipid syndrome (D68.61)

Clinical Validation Requirements

  • Factor V Leiden PCR positive
  • APC resistance ratio <2.0

Code-Specific Risks

  • Misdiagnosis without genetic confirmation

Coding Notes

  • Ensure genetic confirmation is documented.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Acute DVT

I82.4xx
Use alongside D68.51 if patient has an active DVT.

Long-term anticoagulant use

Z79.01
Document if patient is on long-term anticoagulant therapy.

Adverse effect of anticoagulants

T45.515A
Use to specify adverse effect causing bleeding.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Other primary thrombophilia

D68.59
Use D68.59 for other inherited thrombophilias like prothrombin gene mutation.

Activated protein C resistance

D68.51
Use D68.51 specifically for Factor V Leiden.

Adverse effect of anticoagulants

T45.515A
Use T45.515A for adverse effects not directly causing hemorrhage.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Clotting Disorder to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code D68.51.

Impact

Clinical: May lead to inappropriate treatment., Regulatory: Non-compliance with documentation standards., Financial: Potential for denied claims.

Mitigation Strategy

Specify hereditary or acquired thrombophilia., Include genetic test results.

Impact

Reimbursement: Incorrect coding may lead to denied claims., Compliance: Non-compliance with ICD-10 guidelines., Data Quality: Inaccurate patient records.

Mitigation Strategy

Code I82.411 first, then D68.59 only if thrombophilia is documented.

Impact

Reimbursement: May result in claim rejections., Compliance: Violation of coding standards., Data Quality: Misleading clinical data.

Mitigation Strategy

Use only if no definitive coagulopathy exists.

Impact

High risk of audit if thrombophilia is coded without documented genetic confirmation.

Mitigation Strategy

Require genetic test documentation before coding.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Clotting Disorder, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Clotting Disorder

Use these documentation templates to ensure complete and accurate documentation for Clotting Disorder. These templates include all required elements for proper coding and billing.

Hematology Progress Note

Specialty: Hematology

Required Elements

  • Diagnosis
  • Genetic Confirmation
  • Current Anticoagulation
  • Active Complications
  • Plan

Example Documentation

1. Diagnosis: Hereditary Factor V Leiden thrombophilia (D68.51) 2. Genetic Confirmation: F5 gene mutation detected via PCR 3. Current Anticoagulation: Rivaroxaban 20 mg daily 4. Active Complications: No acute thrombosis; stable on rivaroxaban 5. Plan: D-dimer q6mo, avoid estrogen-based OCPs

Examples: Poor vs. Good Documentation

Poor Documentation Example
Clotting disorder, on blood thinners.
Good Documentation Example
Hereditary Factor V Leiden thrombophilia (confirmed 2023 PCR), stable on apixaban 5 mg BID for DVT prophylaxis. Last D-dimer 350 ng/mL (2025-03-01). No bleeding complications.
Explanation
The good example provides specific diagnosis, genetic confirmation, treatment details, and monitoring plan.

Need help with ICD-10 coding for Clotting Disorder? Ask your questions below.

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