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ICD-10 Coding for Colony-Stimulating Factor(D70.1, J2505)

Complete ICD-10-CM coding and documentation guide for Colony-Stimulating Factor. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

CSFG-CSFGM-CSF

Related ICD-10 Code Ranges

Complete code families applicable to Colony-Stimulating Factor

D70-D77Primary Range

Other disorders of blood and blood-forming organs

Includes codes for neutropenia and related conditions treated with CSFs.

Drugs used for colony-stimulating factor administration

Includes specific codes for different CSF agents like filgrastim and pegfilgrastim.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
D70.1Agranulocytosis secondary to cancer chemotherapyUse when neutropenia is a result of chemotherapy treatment.
  • ANC < 500/mm³
  • Chemotherapy regimen documentation
J2505Injection, pegfilgrastim, 6 mgUse for prophylactic administration post-chemotherapy.
  • Documented use post-chemotherapy
  • Prophylactic use for neutropenia

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for chemotherapy-induced neutropenia

Essential facts and insights about Colony-Stimulating Factor

The ICD-10 code for chemotherapy-induced neutropenia is D70.1, used when neutropenia results from chemotherapy.

Primary ICD-10-CM Codes for colony-stimulating factor

Agranulocytosis secondary to cancer chemotherapy
Billable Code

Decision Criteria

clinical Criteria

  • ANC < 500/mm³ post-chemotherapy

Applicable To

  • Chemotherapy-induced neutropenia

Excludes

  • Neutropenia due to other causes

Clinical Validation Requirements

  • ANC < 500/mm³
  • Chemotherapy regimen documentation

Code-Specific Risks

  • Incorrect sequencing with primary malignancy codes

Coding Notes

  • Ensure proper sequencing with cancer codes.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Injection, filgrastim, 1 microgram

J1442
Use for administration of filgrastim in conjunction with D70.1.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Other neutropenia

D70.2
Use for neutropenia not related to chemotherapy.

Injection, filgrastim, 1 microgram

J1442
Use for filgrastim rather than pegfilgrastim.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Colony-Stimulating Factor to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code D70.1.

Impact

Clinical: Inadequate justification for CSF use., Regulatory: Non-compliance with documentation standards., Financial: Potential for claim denials.

Mitigation Strategy

Include ANC values in all CSF-related documentation, Use standardized templates

Impact

Reimbursement: May result in claim denials or reduced payment., Compliance: Non-compliance with ICD-10 guidelines., Data Quality: Inaccurate clinical data representation.

Mitigation Strategy

Always sequence underlying malignancy first, followed by neutropenia and CSF administration codes.

Impact

Inadequate documentation of CSF use can lead to audit findings.

Mitigation Strategy

Use detailed templates and ensure all required elements are documented.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Colony-Stimulating Factor, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Colony-Stimulating Factor

Use these documentation templates to ensure complete and accurate documentation for Colony-Stimulating Factor. These templates include all required elements for proper coding and billing.

CSF administration post-chemotherapy

Specialty: Oncology

Required Elements

  • Indication for CSF
  • Agent and dosage
  • Timing post-chemotherapy
  • ANC values

Example Documentation

Pegfilgrastim 6 mg SQ administered 24hr post-cycle 1 of AC regimen for FN prophylaxis.

Examples: Poor vs. Good Documentation

Poor Documentation Example
G-CSF given post-chemo.
Good Documentation Example
Pegfilgrastim 6 mg SQ administered 24hr post-cycle 1 of AC regimen for FN prophylaxis due to prior ANC nadir 200/mm³.
Explanation
The good example specifies the agent, dosage, timing, and clinical rationale.

Need help with ICD-10 coding for Colony-Stimulating Factor? Ask your questions below.

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