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ICD-10 Coding for Elevated Creatine Phosphokinase(R74.8, M62.82)

Complete ICD-10-CM coding and documentation guide for Elevated Creatine Phosphokinase. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

Elevated CPKHyperCKemia

Related ICD-10 Code Ranges

Complete code families applicable to Elevated Creatine Phosphokinase

R70-R79Primary Range

Abnormal findings on examination of blood, without diagnosis

This range includes codes for abnormal levels of serum enzymes, including CPK.

Disorders of muscles

This range includes codes for muscle disorders that may cause elevated CPK.

Ischemic heart diseases

This range includes codes for myocardial infarction, which can cause elevated CPK.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
R74.8Abnormal levels of other serum enzymesUse when CPK is elevated without a definitive diagnosis.
  • Documented CPK level
  • Exclusion of specific causes such as MI or rhabdomyolysis
M62.82RhabdomyolysisUse when rhabdomyolysis is confirmed with lab findings.
  • CPK >5,000 U/L
  • Presence of myoglobinuria

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for elevated creatine phosphokinase

Essential facts and insights about Elevated Creatine Phosphokinase

The ICD-10 code for elevated creatine phosphokinase without a definitive diagnosis is R74.8.

Primary ICD-10-CM Codes for elevated creatine phosphokinase

Abnormal levels of other serum enzymes
Billable Code

Decision Criteria

clinical Criteria

  • CPK level documented without definitive diagnosis

documentation Criteria

  • Exclusion of myocardial infarction or rhabdomyolysis

Applicable To

  • Elevated creatine kinase

Excludes

  • Rhabdomyolysis (M62.82)
  • Myocardial infarction (I21.-)

Clinical Validation Requirements

  • Documented CPK level
  • Exclusion of specific causes such as MI or rhabdomyolysis

Code-Specific Risks

  • Misclassification if underlying cause is not ruled out

Coding Notes

  • Ensure documentation specifies no definitive cause for CPK elevation.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Long term (current) use of statins

Z79.82
Use when CPK elevation is associated with statin use.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Rhabdomyolysis

M62.82
Use when CPK >5,000 U/L with myoglobinuria or acute kidney injury.

Acute myocardial infarction, unspecified

I21.9
Use only with documented STEMI/NSTEMI and troponin elevation.

Abnormal levels of other serum enzymes

R74.8
Use when no specific cause like rhabdomyolysis is identified.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Elevated Creatine Phosphokinase to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code R74.8.

Impact

Clinical: Potential misdiagnosis of cardiac event., Regulatory: Non-compliance with coding standards., Financial: Possible claim denials.

Mitigation Strategy

Always document exclusion of MI when CPK is elevated., Use templates to ensure comprehensive documentation.

Impact

Reimbursement: Incorrect coding can lead to denied claims., Compliance: Non-compliance with coding guidelines., Data Quality: Inaccurate clinical data representation.

Mitigation Strategy

Ensure MI is documented with troponin elevation before coding.

Impact

Incorrectly coding CPK elevation as myocardial infarction.

Mitigation Strategy

Ensure thorough documentation of exclusion criteria.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Elevated Creatine Phosphokinase, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Elevated Creatine Phosphokinase

Use these documentation templates to ensure complete and accurate documentation for Elevated Creatine Phosphokinase. These templates include all required elements for proper coding and billing.

Unexplained CPK elevation

Specialty: Internal Medicine

Required Elements

  • CPK level
  • Exclusion of specific causes
  • Follow-up plan

Examples: Poor vs. Good Documentation

Poor Documentation Example
Elevated CPK, monitor.
Good Documentation Example
CPK 1,200 U/L, no recent trauma or statin use, follow-up in 4 weeks.
Explanation
The good example provides specific CPK level and rules out common causes.

Need help with ICD-10 coding for Elevated Creatine Phosphokinase? Ask your questions below.

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