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ICD-10 Coding for Elevated Homocysteine(R79.83, E72.11, E72.12)

Complete ICD-10-CM coding and documentation guide for Elevated Homocysteine. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

HyperhomocysteinemiaHigh Homocysteine Levels

Related ICD-10 Code Ranges

Complete code families applicable to Elevated Homocysteine

R70-R79Primary Range

Abnormal findings on examination of blood, without diagnosis

Includes R79.83 for abnormal blood amino-acid levels, specifically hyperhomocysteinemia.

Metabolic disorders

Includes E72.11 for homocystinuria and E72.12 for MTHFR deficiency.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
R79.83Abnormal findings of blood amino-acid levelsUse when elevated homocysteine is detected without a specific genetic cause.
  • Homocysteine level >15 μmol/L
  • Exclusion of genetic causes
E72.11HomocystinuriaUse when homocystinuria is confirmed by genetic testing.
  • Genetic confirmation of CBS deficiency
  • Homocysteine level >13.9 μmol/L
E72.12MTHFR deficiencyUse when MTHFR deficiency is confirmed by genetic testing.
  • Genetic testing showing MTHFR polymorphism
  • Homocysteine level 15-30 μmol/L

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for elevated homocysteine

Essential facts and insights about Elevated Homocysteine

The ICD-10 code for elevated homocysteine is R79.83, used for abnormal blood amino-acid levels without a specific genetic cause.

Primary ICD-10-CM Codes for elevated homocysteine

Abnormal findings of blood amino-acid levels
Billable Code

Decision Criteria

clinical Criteria

  • Homocysteine level >15 μmol/L without genetic confirmation.

Applicable To

  • Hyperhomocysteinemia

Excludes

Clinical Validation Requirements

  • Homocysteine level >15 μmol/L
  • Exclusion of genetic causes

Code-Specific Risks

  • Confusion with genetic disorders like homocystinuria.

Coding Notes

  • Ensure documentation specifies homocysteine levels and excludes genetic causes.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Vitamin B12 deficiency anemia

D51.0
Use when elevated homocysteine is due to B12 deficiency.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Homocystinuria

E72.11
Confirmed genetic disorder with CBS deficiency.

Abnormal findings of blood amino-acid levels

R79.83
No genetic confirmation of CBS deficiency.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Elevated Homocysteine to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code R79.83.

Impact

Clinical: Inadequate data for clinical management., Regulatory: Potential audit issues., Financial: Denied claims due to insufficient documentation.

Mitigation Strategy

Train staff on documentation standards., Use templates to ensure completeness.

Impact

Reimbursement: Incorrect DRG assignment leading to reimbursement issues., Compliance: Non-compliance with coding guidelines., Data Quality: Inaccurate clinical data affecting patient care.

Mitigation Strategy

Verify genetic testing results to confirm homocystinuria.

Impact

Failure to document genetic test results for homocystinuria.

Mitigation Strategy

Implement checklist for genetic testing documentation.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Elevated Homocysteine, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Elevated Homocysteine

Use these documentation templates to ensure complete and accurate documentation for Elevated Homocysteine. These templates include all required elements for proper coding and billing.

Primary Care Evaluation

Specialty: Primary Care

Required Elements

  • Homocysteine level
  • Nutritional status
  • Genetic test results

Example Documentation

Assessment: Elevated homocysteine (R79.83) with level 24.8 μmol/L. B12 and folate levels normal. No genetic disorder confirmed.

Examples: Poor vs. Good Documentation

Poor Documentation Example
High homocysteine noted.
Good Documentation Example
Fasting homocysteine 24.8 μmol/L, B12 450 pg/mL, folate 8.2 ng/mL, genetic testing negative.
Explanation
The good example provides specific lab values and excludes genetic causes.

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