ICD-10 Coding for Factor V Leiden(D68.59, D68.51)
Complete ICD-10-CM coding and documentation guide for Factor V Leiden. Includes clinical validation requirements, documentation requirements, and coding pitfalls.
Also known as:
Related ICD-10 Code Ranges
Complete code families applicable to Factor V Leiden
D68.5-D68.6Primary Range
Other coagulation defects
This range includes codes for hereditary thrombophilia and activated protein C resistance, which are relevant for Factor V Leiden.
Embolism and thrombosis of lower extremity veins
Used for coding deep vein thrombosis (DVT) which can occur due to Factor V Leiden.
Code Comparison: When to Use Each Code
Compare key differences between these codes to ensure accurate selection
| Code | Description | When to Use | Key Documentation |
|---|---|---|---|
| D68.59 | Other primary thrombophilia | Use when genetic testing confirms Factor V Leiden mutation causing thrombophilia. |
|
| D68.51 | Activated protein C resistance | Use when APC resistance is documented without genetic confirmation of Factor V Leiden. |
|
Clinical Decision Support
Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.
Key Information: ICD-10 code for Factor V Leiden
Essential facts and insights about Factor V Leiden
Primary ICD-10-CM Codes for factor vomiting leiden
Decision Criteria
clinical Criteria
- Genetic testing confirms Factor V Leiden mutation.
documentation Criteria
- Documentation specifies hereditary thrombophilia due to Factor V Leiden.
Applicable To
- Hereditary thrombophilia due to Factor V Leiden
Excludes
- Antiphospholipid syndrome (D68.62)
Clinical Validation Requirements
- Genetic confirmation via PCR for F5 mutation
- Documentation of hereditary thrombophilia
Code-Specific Risks
- Misuse for acquired thrombophilia
- Failure to document genetic confirmation
Coding Notes
- Ensure documentation specifies hereditary thrombophilia due to Factor V Leiden mutation.
D68.51 - Activated protein C resistance
Use when APC resistance is documented without genetic confirmation of Factor V Leiden.
Applicable To
- APC resistance without genetic confirmation
Excludes
- Hereditary thrombophilia due to Factor V Leiden (D68.59)
Clinical Validation Requirements
- Functional APC resistance assay
Coding Notes
Ensure documentation specifies APC resistance without genetic confirmation.
Ancillary Codes
Additional codes that should be used in conjunction with the main diagnosis codes when applicable.
Acute embolism and thrombosis of unspecified deep veins of lower extremity
I82.40Differential Codes
Alternative codes to consider when ruling out similar conditions to the primary diagnosis.
Documentation & Coding Risks
Avoid these common documentation and coding issues when documenting Factor V Leiden to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code D68.59.
Impact
Clinical: Leads to misdiagnosis and inappropriate treatment., Regulatory: Non-compliance with documentation standards., Financial: Potential claim denials due to insufficient documentation.
Mitigation Strategy
Use specific terms like 'Factor V Leiden mutation', Document genetic test results
Impact
Reimbursement: Incorrect coding can lead to denied claims., Compliance: Non-compliance with coding guidelines., Data Quality: Inaccurate clinical data representation.
Mitigation Strategy
Ensure genetic confirmation and documentation specify Factor V Leiden.
Impact
Failure to link Factor V Leiden to anticoagulant therapy.
Mitigation Strategy
Ensure documentation specifies the indication for anticoagulation.
Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.
Frequently Asked Questions
Common questions about ICD-10 coding for Factor V Leiden, with expert answers to help guide accurate code selection and documentation.
Documentation Templates for Factor V Leiden
Use these documentation templates to ensure complete and accurate documentation for Factor V Leiden. These templates include all required elements for proper coding and billing.
Thrombophilia workup
Specialty: HematologyRequired Elements
- Patient history
- Genetic testing results
- Current medications
- Family history
Example Documentation
Examples: Poor vs. Good Documentation
Poor Documentation Example
Good Documentation Example
Explanation
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