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ICD-10 Coding for Fever of Unknown Origin(R50.9, R50.2)

Complete ICD-10-CM coding and documentation guide for Fever of Unknown Origin. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

FUOPyrexia of Unknown Origin

Related ICD-10 Code Ranges

Complete code families applicable to Fever of Unknown Origin

R50Primary Range

Fever of other and unknown origin

This range includes codes for fever conditions where the origin is not immediately identifiable, including FUO.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
R50.9Fever, unspecifiedUse when fever persists for ≥3 weeks without an identifiable cause after thorough evaluation.
  • Documented fever ≥100.9°F for ≥3 weeks
  • Negative blood cultures and imaging studies
  • No identifiable cause after extensive workup
R50.2Drug-induced feverUse when fever is directly linked to drug intake.
  • Fever linked to recent drug administration
  • Resolution upon drug discontinuation

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for fever of unknown origin

Essential facts and insights about Fever of Unknown Origin

The ICD-10 code for fever of unknown origin is R50.9, used when fever persists for over 3 weeks without an identifiable cause.

Primary ICD-10-CM Codes for fever of unknown origin

Fever, unspecified
Billable Code

Decision Criteria

clinical Criteria

  • Fever persists ≥3 weeks with no identified cause.

documentation Criteria

  • Detailed records of fever pattern and negative diagnostic tests.

Applicable To

  • Fever of unknown origin

Excludes

  • Fever due to known conditions (e.g., infections, autoimmune diseases)

Clinical Validation Requirements

  • Documented fever ≥100.9°F for ≥3 weeks
  • Negative blood cultures and imaging studies
  • No identifiable cause after extensive workup

Code-Specific Risks

  • Incorrectly using R50.9 when an underlying condition is identified.

Coding Notes

  • Ensure documentation supports the duration and extent of the fever and workup.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

HIV disease

B20
Use if FUO is related to HIV.

Other specified disorders of white blood cells

D72.89
Use if leukocytosis is present.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Other specified fever

R50.8
Use R50.8 for specified fevers not meeting FUO criteria.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Fever of Unknown Origin to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code R50.9.

Impact

Clinical: Leads to misdiagnosis or delayed treatment., Regulatory: Fails to meet coding standards., Financial: Potential for denied claims.

Mitigation Strategy

Ensure detailed fever history is recorded., Include all diagnostic tests performed.

Impact

Reimbursement: Incorrect DRG assignment may occur., Compliance: Non-compliance with coding guidelines., Data Quality: Inaccurate clinical data representation.

Mitigation Strategy

Code the underlying condition first, followed by R50.9 if needed.

Impact

Failure to code underlying conditions first.

Mitigation Strategy

Regular training on ICD-10 sequencing rules.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Fever of Unknown Origin, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Fever of Unknown Origin

Use these documentation templates to ensure complete and accurate documentation for Fever of Unknown Origin. These templates include all required elements for proper coding and billing.

Inpatient FUO Workup

Specialty: Internal Medicine

Required Elements

  • Fever pattern documentation
  • Negative diagnostic tests
  • Therapeutic trials

Example Documentation

Patient presents with FUO: daily fevers 101°F–103°F for 24 days; negative CT abdomen, 3 sets blood cultures, CRP 85 mg/L.

Examples: Poor vs. Good Documentation

Poor Documentation Example
Fever of unknown origin.
Good Documentation Example
Daily fevers 101°F–103°F for 24 days; negative CT abdomen, 3 sets blood cultures, CRP 85 mg/L.
Explanation
The good example provides specific details on fever pattern and diagnostic workup.

Need help with ICD-10 coding for Fever of Unknown Origin? Ask your questions below.

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