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ICD-10 Coding for Gram-negative Sepsis(A41.50, A41.51, A41.58)

Complete ICD-10-CM coding and documentation guide for Gram-negative Sepsis. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

Gram-negative bacteremiaGram-negative septicemia

Related ICD-10 Code Ranges

Complete code families applicable to Gram-negative Sepsis

A41.5Primary Range

Sepsis due to Gram-negative organisms

This range covers all sepsis cases caused by Gram-negative bacteria, including specific organisms like E. coli and Klebsiella.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
A41.50Unspecified Gram-negative sepsisUse when the specific Gram-negative organism is not identified.
  • Positive blood culture for Gram-negative organism
  • Elevated lactate levels
  • Organ dysfunction evidence
A41.51Sepsis due to Escherichia coliUse when E. coli is confirmed as the causative organism.
  • Positive blood culture for E. coli
  • Elevated lactate levels
  • Organ dysfunction evidence
A41.58Sepsis due to other specified Gram-negative organismsUse when a specific Gram-negative organism other than E. coli is identified.
  • Positive blood culture for specified Gram-negative organism
  • Elevated lactate levels
  • Organ dysfunction evidence

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for gram negative sepsis

Essential facts and insights about Gram-negative Sepsis

The ICD-10 code for unspecified gram-negative sepsis is A41.50. Specific codes like A41.51 for E. coli are used when the organism is identified.

Primary ICD-10-CM Codes for gram negative sepsis

Unspecified Gram-negative sepsis
Billable Code

Decision Criteria

clinical Criteria

  • Positive blood culture for Gram-negative organism

documentation Criteria

  • Documentation of 'Gram-negative' in the diagnosis

Applicable To

  • Sepsis due to unspecified Gram-negative organism

Excludes

Clinical Validation Requirements

  • Positive blood culture for Gram-negative organism
  • Elevated lactate levels
  • Organ dysfunction evidence

Code-Specific Risks

  • Risk of under-coding if specific organism is later identified.

Coding Notes

  • Ensure documentation specifies 'Gram-negative' even if the organism is unspecified.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Severe sepsis with septic shock

R65.21
Use to indicate septic shock in conjunction with A41.50.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Sepsis, unspecified organism

A41.9
Use A41.9 when the organism type (Gram-positive or Gram-negative) is not specified.

Sepsis due to other specified Gram-negative organisms

A41.58
Use A41.58 for other specified Gram-negative organisms like Klebsiella.

Sepsis due to Escherichia coli

A41.51
Use A41.51 when E. coli is the causative organism.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Gram-negative Sepsis to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code A41.50.

Impact

Clinical: May lead to inappropriate treatment decisions., Regulatory: Non-compliance with coding standards., Financial: Potential loss of reimbursement due to incorrect coding.

Mitigation Strategy

Ensure culture results are reviewed and documented., Use specific terminology linking organism to sepsis.

Impact

Reimbursement: Incorrect coding can lead to lower DRG assignment and reduced reimbursement., Compliance: Non-compliance with coding guidelines., Data Quality: Inaccurate data for clinical and research purposes.

Mitigation Strategy

Document the specific organism causing the sepsis, such as E. coli.

Impact

Reimbursement: Incorrect sequencing can affect DRG assignment., Compliance: Violates ICD-10 sequencing rules., Data Quality: Impacts accuracy of clinical data.

Mitigation Strategy

Always sequence sepsis first if present on admission.

Impact

Failure to document specific organism can lead to audit findings.

Mitigation Strategy

Implement a checklist for organism documentation in sepsis cases.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Gram-negative Sepsis, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Gram-negative Sepsis

Use these documentation templates to ensure complete and accurate documentation for Gram-negative Sepsis. These templates include all required elements for proper coding and billing.

Gram-negative sepsis due to E. coli

Specialty: Infectious Disease

Required Elements

  • Positive blood culture for E. coli
  • Documentation of sepsis symptoms
  • Organ dysfunction evidence

Example Documentation

Patient presents with sepsis due to E. coli bacteremia, confirmed by positive blood culture. Symptoms include fever, tachycardia, and hypotension. Acute kidney injury noted with creatinine 2.4 mg/dL.

Examples: Poor vs. Good Documentation

Poor Documentation Example
Sepsis with UTI.
Good Documentation Example
Sepsis due to E. coli bacteremia originating from urinary tract infection.
Explanation
The good example specifies the organism and links it to the infection source, meeting documentation requirements.

Need help with ICD-10 coding for Gram-negative Sepsis? Ask your questions below.

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