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ICD-10 Coding for Hepatocellular Carcinoma(C22.0, C22.9)

Complete ICD-10-CM coding and documentation guide for Hepatocellular Carcinoma. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

Liver CancerHCCprimary liver cancer

Related ICD-10 Code Ranges

Complete code families applicable to Hepatocellular Carcinoma

C22.0-C22.9Primary Range

Malignant neoplasms of liver and intrahepatic bile ducts

This range includes codes for primary liver cancers, including hepatocellular carcinoma.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
C22.0Liver cell carcinomaUse when imaging or biopsy confirms hepatocellular carcinoma.
  • Imaging showing arterial hypervascularity and portal/delayed phase washout
  • Biopsy confirming hepatocellular origin
C22.9Malignant neoplasm of liver, unspecifiedUse when liver malignancy is suspected but not yet confirmed as HCC.
  • Use when imaging suggests malignancy but histology is pending

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for hepatocellular carcinoma

Essential facts and insights about Hepatocellular Carcinoma

The ICD-10 code for hepatocellular carcinoma is C22.0, used when confirmed by imaging or biopsy.

Primary ICD-10-CM Codes for hepatocellular carcinoma

Liver cell carcinoma
Billable Code

Decision Criteria

clinical Criteria

  • Confirmed hepatocellular carcinoma via imaging or biopsy

Applicable To

  • Hepatocellular carcinoma

Excludes

  • Cholangiocarcinoma (C22.1)

Clinical Validation Requirements

  • Imaging showing arterial hypervascularity and portal/delayed phase washout
  • Biopsy confirming hepatocellular origin

Code-Specific Risks

  • Incorrectly coding without proper imaging or biopsy confirmation

Coding Notes

  • Ensure imaging or biopsy confirms diagnosis before coding.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Chronic viral hepatitis C

B18.2
Use when HCC is associated with chronic hepatitis C.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Intrahepatic bile duct carcinoma

C22.1
Presence of biliary dilation and positive CK19 staining

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Hepatocellular Carcinoma to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code C22.0.

Impact

Clinical: Misrepresentation of patient condition., Regulatory: Non-compliance with coding standards., Financial: Potential for claim denials.

Mitigation Strategy

Confirm diagnosis with imaging or biopsy before coding., Review documentation for specificity.

Impact

Reimbursement: Incorrect sequencing can lead to denied claims., Compliance: Non-compliance with ICD-10 coding guidelines., Data Quality: Inaccurate clinical data representation.

Mitigation Strategy

Follow CMS etiology/manifestation rules to sequence underlying conditions first.

Impact

Incorrect sequencing of HCC and underlying conditions.

Mitigation Strategy

Educate coding staff on proper sequencing rules.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Hepatocellular Carcinoma, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Hepatocellular Carcinoma

Use these documentation templates to ensure complete and accurate documentation for Hepatocellular Carcinoma. These templates include all required elements for proper coding and billing.

Oncology Progress Note

Specialty: Oncology

Required Elements

  • Tumor characteristics
  • Liver function
  • Treatment plan

Example Documentation

**Assessment:** 1. Hepatocellular carcinoma, stage BCLC B - 3 enhancing lesions (2.5cm, 1.8cm, 1.2cm) - CP-A6, ECOG 1 2. Chronic hepatitis C (Genotype 1a, VL undetectable) **Plan:** - [ ] Continue lenvatinib 8mg daily - [ ] Schedule TACE for dominant lesion - [ ] Monitor for hand-foot syndrome (current grade 1) - [ ] Repeat triple-phase CT in 8 weeks

Examples: Poor vs. Good Documentation

Poor Documentation Example
HCC stable.
Good Documentation Example
HCC status: 2 lesions (2.1cm and 1.8cm) show no interval growth on contrast-enhanced MRI. Continue sorafenib 400mg BID. Next AFP in 3 months.
Explanation
The good example includes specific tumor measurements, treatment plan, and follow-up schedule.

Need help with ICD-10 coding for Hepatocellular Carcinoma? Ask your questions below.

Ask about any ICD-10 CM code, or paste a medical note

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