ICD-10 Coding for Homocysteine Disorders(E72.11, R79.83, E72.12)
Complete ICD-10-CM coding and documentation guide for Homocysteine Disorders. Includes clinical validation requirements, documentation requirements, and coding pitfalls.
Also known as:
Related ICD-10 Code Ranges
Complete code families applicable to Homocysteine Disorders
E72.1-E72.12Primary Range
Disorders of sulfur-bearing amino-acid metabolism
This range includes genetic and acquired disorders affecting homocysteine metabolism.
Abnormal findings of blood amino-acid levels
Used for elevated homocysteine levels without a specified genetic disorder.
Code Comparison: When to Use Each Code
Compare key differences between these codes to ensure accurate selection
| Code | Description | When to Use | Key Documentation |
|---|---|---|---|
| E72.11 | Homocystinuria | Use when genetic testing confirms homocystinuria. |
|
| R79.83 | Abnormal blood amino-acid level | Use for elevated homocysteine levels without genetic disorder. |
|
| E72.12 | MTHFR deficiency | Use for confirmed MTHFR mutation affecting homocysteine metabolism. |
|
Clinical Decision Support
Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.
Key Information: ICD-10 code for elevated homocysteine
Essential facts and insights about Homocysteine Disorders
Primary ICD-10-CM Codes for homocysteine
Decision Criteria
clinical Criteria
- Genetic testing confirms CBS mutation.
Applicable To
- Cystathionine beta-synthase deficiency
Excludes
- Hyperhomocysteinemia without genetic confirmation
Clinical Validation Requirements
- Plasma homocysteine >100 µmol/L
- CBS gene mutation analysis
Code-Specific Risks
- Incorrectly coding without genetic confirmation.
Coding Notes
- Ensure genetic confirmation is documented.
R79.83 - Abnormal blood amino-acid level
Use for elevated homocysteine levels without genetic disorder.
Applicable To
- Hyperhomocysteinemia
Excludes
- Homocystinuria
Clinical Validation Requirements
- Homocysteine 15-100 µmol/L
- Normal CBS/MTHFR
Coding Notes
Document specific cause of elevated homocysteine.
E72.12 - MTHFR deficiency
Use for confirmed MTHFR mutation affecting homocysteine metabolism.
Applicable To
- MTHFR mutation
Excludes
- Homocystinuria
Clinical Validation Requirements
- MTHFR C677T mutation testing
Coding Notes
Ensure mutation confirmation is documented.
Ancillary Codes
Additional codes that should be used in conjunction with the main diagnosis codes when applicable.
Documentation & Coding Risks
Avoid these common documentation and coding issues when documenting Homocysteine Disorders to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code E72.11.
Impact
Clinical: Misleading diagnosis leading to inappropriate treatment., Regulatory: Non-compliance with coding standards., Financial: Potential claim rejections.
Mitigation Strategy
Verify genetic testing results, Educate staff on coding guidelines
Impact
Reimbursement: May lead to claim denials., Compliance: Non-compliance with coding guidelines., Data Quality: Inaccurate clinical data representation.
Mitigation Strategy
Ensure genetic testing is documented before using E72.11.
Impact
Risk of coding genetic disorders without confirmation.
Mitigation Strategy
Require genetic test documentation before coding.
Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.
Frequently Asked Questions
Common questions about ICD-10 coding for Homocysteine Disorders, with expert answers to help guide accurate code selection and documentation.
Documentation Templates for Homocysteine Disorders
Use these documentation templates to ensure complete and accurate documentation for Homocysteine Disorders. These templates include all required elements for proper coding and billing.
Progress Note for Hyperhomocysteinemia
Specialty: EndocrinologyRequired Elements
- Assessment of homocysteine levels
- Underlying cause identification
- Treatment plan
Example Documentation
Examples: Poor vs. Good Documentation
Poor Documentation Example
Good Documentation Example
Explanation
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