ICD-10 Coding for Hyperammonemia(E72.4, P74.6, K76.82)
Complete ICD-10-CM coding and documentation guide for Hyperammonemia. Includes clinical validation requirements, documentation requirements, and coding pitfalls.
Also known as:
Related ICD-10 Code Ranges
Complete code families applicable to Hyperammonemia
E72.2-E72.4Primary Range
Disorders of urea cycle metabolism
Includes specific disorders related to hyperammonemia due to urea cycle defects.
Code Comparison: When to Use Each Code
Compare key differences between these codes to ensure accurate selection
| Code | Description | When to Use | Key Documentation |
|---|---|---|---|
| E72.4 | Disorders of ornithine metabolism | Use when there is confirmed ornithine metabolism disorder with hyperammonemia. |
|
| P74.6 | Transitory hyperammonemia of newborn | Use for newborns with transient hyperammonemia resolving within 7 days. |
|
| K76.82 | Hepatic encephalopathy | Use when hyperammonemia is due to liver dysfunction. |
|
Clinical Decision Support
Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.
Key Information: ICD-10 code for hyperammonemia
Essential facts and insights about Hyperammonemia
Primary ICD-10-CM Codes for hyperammonemia
Decision Criteria
clinical Criteria
- Confirmed genetic defect in ornithine metabolism.
Applicable To
- HHH syndrome
Excludes
- Other urea cycle disorders (E72.29)
Clinical Validation Requirements
- Genetic confirmation of ornithine transporter defect
- Elevated ammonia levels
Code-Specific Risks
- Misclassification if genetic testing is not documented.
Coding Notes
- Ensure genetic testing is documented for accurate coding.
P74.6 - Transitory hyperammonemia of newborn
Use for newborns with transient hyperammonemia resolving within 7 days.
Excludes
- Persistent hyperammonemia
Clinical Validation Requirements
- Neonatal onset with ammonia >80 µmol/L
Coding Notes
Ensure documentation specifies neonatal onset and resolution.
K76.82 - Hepatic encephalopathy
Use when hyperammonemia is due to liver dysfunction.
Excludes
- Hyperammonemia coded separately unless specified
Clinical Validation Requirements
- Liver disease with altered mental status and elevated ammonia
Coding Notes
Do not code hyperammonemia separately unless specified.
Ancillary Codes
Additional codes that should be used in conjunction with the main diagnosis codes when applicable.
Hepatic encephalopathy
K76.82Differential Codes
Alternative codes to consider when ruling out similar conditions to the primary diagnosis.
Other urea cycle disorders
E72.29Documentation & Coding Risks
Avoid these common documentation and coding issues when documenting Hyperammonemia to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code E72.4.
Impact
Clinical: Inaccurate diagnosis and treatment., Regulatory: Non-compliance with coding standards., Financial: Potential reimbursement issues.
Mitigation Strategy
Ensure lab results are included in documentation.
Impact
Reimbursement: May affect DRG assignment and reimbursement., Compliance: Non-compliance with coding guidelines., Data Quality: Decreases accuracy of clinical data.
Mitigation Strategy
Ensure genetic or biochemical confirmation is documented.
Impact
Using E72.20 instead of specific codes.
Mitigation Strategy
Ensure genetic testing is documented.
Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.
Frequently Asked Questions
Common questions about ICD-10 coding for Hyperammonemia, with expert answers to help guide accurate code selection and documentation.
Documentation Templates for Hyperammonemia
Use these documentation templates to ensure complete and accurate documentation for Hyperammonemia. These templates include all required elements for proper coding and billing.
Neonatal hyperammonemia
Specialty: PediatricsRequired Elements
- Neonatal onset
- Ammonia levels
- Resolution timeline
Example Documentation
Examples: Poor vs. Good Documentation
Poor Documentation Example
Good Documentation Example
Explanation
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