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ICD-10 Coding for Hypercholesterolemia(E78.00, E78.01, E78.2)

Complete ICD-10-CM coding and documentation guide for Hypercholesterolemia. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

High cholesterolCholesterolemiaelevated cholesterol

Related ICD-10 Code Ranges

Complete code families applicable to Hypercholesterolemia

E78.0-E78.5Primary Range

Disorders of lipoprotein metabolism and other lipidemias

This range includes codes for various types of hyperlipidemia, including hypercholesterolemia.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
E78.00Pure hypercholesterolemia, unspecifiedUse when elevated cholesterol is present without a specific cause or genetic confirmation.
  • LDL ≥190 mg/dL in adults
  • No triglycerides >200 mg/dL
E78.01Familial hypercholesterolemiaUse when genetic testing confirms familial hypercholesterolemia.
  • LDL ≥190 mg/dL
  • Genetic testing confirming LDLR, APOB, or PCSK9 mutation
E78.2Mixed hyperlipidemiaUse when both cholesterol and triglycerides are elevated.
  • LDL ≥160 mg/dL
  • Triglycerides ≥150 mg/dL

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for hypercholesterolemia

Essential facts and insights about Hypercholesterolemia

The ICD-10 code for pure hypercholesterolemia is E78.00, and for familial hypercholesterolemia, it is E78.01.

Primary ICD-10-CM Codes for hypercholesteremia

Pure hypercholesterolemia, unspecified
Billable Code

Decision Criteria

clinical Criteria

  • LDL ≥190 mg/dL with no secondary causes

documentation Criteria

  • Document specific LDL levels and absence of secondary causes

Applicable To

  • Elevated LDL cholesterol without specific cause

Excludes

  • Familial hypercholesterolemia (E78.01)
  • Mixed hyperlipidemia (E78.2)

Clinical Validation Requirements

  • LDL ≥190 mg/dL in adults
  • No triglycerides >200 mg/dL

Code-Specific Risks

  • Misclassification when familial hypercholesterolemia is suspected

Coding Notes

  • Ensure LDL levels are documented and secondary causes are ruled out.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Long term (current) use of insulin

Z79.4
Use to indicate ongoing statin therapy.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Familial hypercholesterolemia

E78.01
Requires genetic testing or specific clinical criteria such as tendon xanthomas.

Mixed hyperlipidemia

E78.2
Presence of both elevated cholesterol and triglycerides.

Pure hypercholesterolemia, unspecified

E78.00
No genetic confirmation or specific familial criteria.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Hypercholesterolemia to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code E78.00.

Impact

Clinical: Potential misdiagnosis of familial hypercholesterolemia., Regulatory: Non-compliance with coding standards., Financial: Possible claim denials or reduced reimbursement.

Mitigation Strategy

Ensure genetic testing is ordered and results are documented., Review family history for early heart disease.

Impact

Reimbursement: Incorrect coding can lead to denied claims or lower reimbursement., Compliance: Non-compliance with coding guidelines., Data Quality: Inaccurate patient records and data reporting.

Mitigation Strategy

Ensure genetic testing or clinical criteria are documented for E78.01.

Impact

Using unspecified codes like E78.5 when specific codes are applicable.

Mitigation Strategy

Ensure specific lab results and clinical criteria are documented.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Hypercholesterolemia, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Hypercholesterolemia

Use these documentation templates to ensure complete and accurate documentation for Hypercholesterolemia. These templates include all required elements for proper coding and billing.

Primary care visit for hypercholesterolemia management

Specialty: Primary Care

Required Elements

  • Patient history
  • Family history
  • Lab results
  • Physical exam findings

Example Documentation

Patient with LDL 210 mg/dL, no secondary causes identified. Diagnosis: Pure hypercholesterolemia (E78.00).

Examples: Poor vs. Good Documentation

Poor Documentation Example
High cholesterol, start statin.
Good Documentation Example
LDL 212 mg/dL x2, no secondary causes. Diagnosis: Pure hypercholesterolemia (E78.00). Rosuvastatin 10 mg initiated.
Explanation
The good example includes specific LDL levels and rules out secondary causes, providing a clear diagnosis and treatment plan.

Need help with ICD-10 coding for Hypercholesterolemia? Ask your questions below.

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