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ICD-10 Coding for Immunodeficiency(D83.0, D84.821)

Complete ICD-10-CM coding and documentation guide for Immunodeficiency. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

Immune DeficiencyImmune System Disorder

Related ICD-10 Code Ranges

Complete code families applicable to Immunodeficiency

D80-D84Primary Range

Immunodeficiencies

This range includes various types of immunodeficiencies, including primary and secondary forms.

Other disorders involving the immune mechanism, not elsewhere classified

This range includes unspecified immune disorders and other immune mechanism disorders.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
D83.0Common Variable Immunodeficiency with predominant abnormalities of B-cell numbers and functionUse when CVID is confirmed by lab tests showing low IgG and poor vaccine response.
  • Serum IgG < 400 mg/dL
  • Absent vaccine response
D84.821Immunodeficiency due to drugsUse when immunodeficiency is directly linked to drug therapy.
  • Documented use of immunosuppressive drugs
  • Clinical evidence of immunodeficiency

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for drug-induced immunodeficiency

Essential facts and insights about Immunodeficiency

The ICD-10 code for drug-induced immunodeficiency is D84.821.

Primary ICD-10-CM Codes for immunodeficiency

Common Variable Immunodeficiency with predominant abnormalities of B-cell numbers and function
Billable Code

Decision Criteria

clinical Criteria

  • Confirmed low IgG levels and poor vaccine response

Applicable To

  • CVID with autoimmunity

Excludes

  • Selective IgA deficiency (D80.2)

Clinical Validation Requirements

  • Serum IgG < 400 mg/dL
  • Absent vaccine response

Code-Specific Risks

  • Misclassification if lab results are not documented.

Coding Notes

  • Ensure lab confirmation of immunodeficiency before coding.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Escherichia coli [E. coli] as the cause of diseases classified elsewhere

B96.2
Use when E. coli infection is present in immunodeficient patients.

Adverse effect of immunosuppressive drugs

T45.1X5A
Use to specify the adverse effect of the drug causing immunodeficiency.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Nonfamilial hypogammaglobulinemia

D80.1
Use D80.1 for hypogammaglobulinemia without the specific features of CVID.

Unspecified disorder of immune mechanism

D89.9
Use D89.9 when the specific cause of immunodeficiency is unknown.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Immunodeficiency to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code D83.0.

Impact

Clinical: May lead to misdiagnosis., Regulatory: Non-compliance with documentation standards., Financial: Potential for claim denials.

Mitigation Strategy

Use specific lab values and clinical findings., Link drug use to immunodeficiency.

Impact

Reimbursement: May lead to reduced reimbursement rates., Compliance: Non-compliance with coding guidelines., Data Quality: Decreases accuracy of health data.

Mitigation Strategy

Use specific codes like D84.821 for drug-induced cases.

Impact

Failure to sequence underlying conditions before immunodeficiency.

Mitigation Strategy

Educate coding staff on proper sequencing rules.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Immunodeficiency, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Immunodeficiency

Use these documentation templates to ensure complete and accurate documentation for Immunodeficiency. These templates include all required elements for proper coding and billing.

Immunology Consult Note

Specialty: Immunology

Required Elements

  • Diagnosis confirmation
  • Lab results
  • Infection history
  • Treatment plan

Example Documentation

Pt with D83.0 (CVID) confirmed by serum IgG 250 mg/dL, IgA < 7 mg/dL, and failure to mount antibody response to pneumococcal vaccine.

Examples: Poor vs. Good Documentation

Poor Documentation Example
Patient has immune issues.
Good Documentation Example
CVID confirmed by serum IgG < 400 mg/dL and poor vaccine response.
Explanation
The good example provides specific lab results and diagnosis confirmation.

Need help with ICD-10 coding for Immunodeficiency? Ask your questions below.

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