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ICD-10 Coding for Leiomyosarcoma(C49.-, C55.9)

Complete ICD-10-CM coding and documentation guide for Leiomyosarcoma. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

LMSSmooth Muscle Sarcoma

Related ICD-10 Code Ranges

Complete code families applicable to Leiomyosarcoma

C49.-Primary Range

Malignant neoplasm of connective and soft tissue

Primary range for coding leiomyosarcoma based on the site of origin in connective or soft tissue.

Malignant neoplasm of uterus, unspecified

Used for uterine leiomyosarcoma, the most common site for this condition.

Secondary and unspecified malignant neoplasm of lymph nodes

Used for metastatic leiomyosarcoma with lymph node involvement.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
C49.-Malignant neoplasm of connective and soft tissueUse when leiomyosarcoma originates in connective or soft tissue.
  • Histopathology confirming smooth muscle differentiation
  • Immunohistochemistry positive for desmin, SMA
C55.9Malignant neoplasm of uterus, unspecifiedUse for leiomyosarcoma originating in the uterus.
  • Histopathology confirming uterine origin
  • Immunohistochemistry positive for smooth muscle markers

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for leiomyosarcoma

Essential facts and insights about Leiomyosarcoma

The ICD-10 code for leiomyosarcoma varies by site: C49.- for soft tissue and C55.9 for uterine, both with morphology code 8890/3.

Primary ICD-10-CM Codes for leiomyosarcoma

Malignant neoplasm of connective and soft tissue
Non-billable Code

Decision Criteria

clinical Criteria

  • Confirmed soft tissue origin via imaging and biopsy.

Applicable To

  • Leiomyosarcoma of soft tissue

Excludes

  • Benign neoplasms of soft tissue

Clinical Validation Requirements

  • Histopathology confirming smooth muscle differentiation
  • Immunohistochemistry positive for desmin, SMA

Code-Specific Risks

  • Misclassification if morphology code is not appended.

Coding Notes

  • Ensure primary site is confirmed through pathology.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Personal history of malignant neoplasm of soft tissue

Z85.3
Use post-resection to indicate history of leiomyosarcoma.

Secondary malignant neoplasm of liver

C78.7
Use for metastatic spread to the liver.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Malignant neoplasm of bone

C41.-
Use C41.- if the primary site is bone, not soft tissue.

Malignant neoplasm of endometrium

C54.1
Use C54.1 if the neoplasm is endometrial, not muscular.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Leiomyosarcoma to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code C49.-.

Impact

Clinical: Misclassification of cancer type., Regulatory: Non-compliance with ICD-10 coding standards., Financial: Potential underpayment due to incorrect DRG.

Mitigation Strategy

Review pathology reports for histological confirmation., Ensure morphology code is appended to primary site code.

Impact

Reimbursement: Incorrect DRG assignment leading to underpayment., Compliance: Non-compliance with coding guidelines., Data Quality: Inaccurate data affecting cancer registries.

Mitigation Strategy

Require pathology stating 'malignant smooth muscle tumor'.

Impact

Failure to include morphology code 8890/3 with primary site code.

Mitigation Strategy

Implement coding audits to ensure morphology codes are used.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Leiomyosarcoma, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Leiomyosarcoma

Use these documentation templates to ensure complete and accurate documentation for Leiomyosarcoma. These templates include all required elements for proper coding and billing.

Primary retroperitoneal leiomyosarcoma

Specialty: Oncology

Required Elements

  • Primary site confirmation
  • Histopathology results
  • Immunohistochemistry markers

Example Documentation

Assessment: Primary retroperitoneal leiomyosarcoma (C49.4, 8890/3). Plan: Doxorubicin + olaratumab.

Examples: Poor vs. Good Documentation

Poor Documentation Example
Abdominal sarcoma
Good Documentation Example
High-grade leiomyosarcoma arising from retroperitoneal soft tissue, confirmed via CT-guided biopsy (SMA+, desmin+).
Explanation
The good example specifies the histological type and site, essential for accurate coding.

Need help with ICD-10 coding for Leiomyosarcoma? Ask your questions below.

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