Back to HomeBeta

ICD-10 Coding for Mismatch Repair Testing(Z15.89, C18.9)

Complete ICD-10-CM coding and documentation guide for Mismatch Repair Testing. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

MMR TestingLynch Syndrome TestingMMR Antibody Titer

Related ICD-10 Code Ranges

Complete code families applicable to Mismatch Repair Testing

Z80-Z84Primary Range

Family history of primary malignant neoplasm

Used for coding family history related to genetic testing for Lynch syndrome.

Malignant neoplasms of colon, rectum, and anus

Used when coding for colorectal cancer associated with mismatch repair testing.

Genetic susceptibility to disease

Used for coding genetic susceptibility, such as Lynch syndrome.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
Z15.89Genetic susceptibility to other diseaseUse when genetic testing for Lynch syndrome is performed.
  • Family history of Lynch syndrome
  • Genetic counseling documentation
C18.9Malignant neoplasm of colon, unspecifiedUse when mismatch repair testing is performed on a colorectal tumor.
  • Pathology report confirming colorectal cancer

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for MMR titer

Essential facts and insights about Mismatch Repair Testing

The ICD-10 code for MMR titer testing depends on the context: use Z71.85 for immunity checks or Z20.89 for exposure.

Primary ICD-10-CM Codes for mismatch repair titer

Genetic susceptibility to other disease
Billable Code

Decision Criteria

clinical Criteria

  • Presence of family history of Lynch syndrome

Applicable To

  • Lynch syndrome genetic testing

Excludes

  • Personal history of malignant neoplasm (Z85.-)

Clinical Validation Requirements

  • Family history of Lynch syndrome
  • Genetic counseling documentation

Code-Specific Risks

  • Ensure linkage to family history or neoplasm code.

Coding Notes

  • Ensure genetic testing is documented with appropriate family history.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Malignant neoplasm of colon, unspecified

C18.9
Use when testing is due to a confirmed neoplasm.

Genetic susceptibility to other disease

Z15.89
Use when genetic testing is performed.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Family history of malignant neoplasm of digestive organs

Z80.0
Use when family history is the primary reason for testing.

Malignant neoplasm of rectosigmoid junction

C19
Use when the tumor is located at the rectosigmoid junction.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Mismatch Repair Testing to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code Z15.89.

Impact

Clinical: May lead to unnecessary testing., Regulatory: Non-compliance with documentation standards., Financial: Potential claim denials.

Mitigation Strategy

Always include a clear reason for testing in the patient's record.

Impact

Clinical: Misrepresentation of patient's genetic risk., Regulatory: Non-compliance with coding guidelines., Financial: Denial of reimbursement for genetic testing.

Mitigation Strategy

Ensure genetic tests are linked to family history or neoplasm codes.

Impact

Reimbursement: Incorrect coding may lead to claim denials., Compliance: Non-compliance with ICD-10 guidelines., Data Quality: Inaccurate patient records.

Mitigation Strategy

Use Z71.85 for immunization safety counseling or Z20.89 for exposure.

Impact

Reimbursement: Potential denial of genetic testing claims., Compliance: Failure to meet coding standards., Data Quality: Incomplete genetic testing documentation.

Mitigation Strategy

Ensure genetic tests are coded with relevant neoplasm or family history codes.

Impact

Risk of audit due to improper coding of MMR titer tests.

Mitigation Strategy

Ensure all tests are linked to a documented medical necessity.

Impact

Risk of audit due to lack of linkage to family history or neoplasm.

Mitigation Strategy

Document family history and link to genetic testing codes.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Mismatch Repair Testing, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Mismatch Repair Testing

Use these documentation templates to ensure complete and accurate documentation for Mismatch Repair Testing. These templates include all required elements for proper coding and billing.

Pre-employment MMR Immunity Check

Specialty: Occupational Medicine

Required Elements

  • Patient demographics
  • Reason for immunity testing
  • Specific tests ordered

Example Documentation

Patient requires MMR immunity verification for healthcare worker credentialing.

Examples: Poor vs. Good Documentation

Poor Documentation Example
MMR titers ordered.
Good Documentation Example
28yo female presents for pre-employment physical. No record of childhood MMR vaccination. Orders: Measles IgG, Mumps IgG, Rubella IgG to assess immune status prior to hospital orientation.
Explanation
The good example provides context and justification for testing.

Lynch Syndrome Genetic Testing

Specialty: Oncology

Required Elements

  • Patient demographics
  • Family history of cancer
  • Specific genetic tests ordered

Examples: Poor vs. Good Documentation

Poor Documentation Example
Lynch testing ordered.
Good Documentation Example
55M with newly diagnosed poorly differentiated colorectal adenocarcinoma. Tumor sent for mismatch repair IHC (MLH1, MSH2, MSH6, PMS2) to evaluate for microsatellite instability status given family history of endometrial cancer in sister.
Explanation
The good example links the test to a specific clinical scenario and family history.

Need help with ICD-10 coding for Mismatch Repair Testing? Ask your questions below.

Ask about any ICD-10 CM code, or paste a medical note

We build tools for
clinician happiness.

Learn More at Freed.ai
Back to HomeBeta

Built by Freed

Try Freed for free for 7 days.

Learn more