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ICD-10 Coding for Multiple Sclerosis(G35)

Complete ICD-10-CM coding and documentation guide for Multiple Sclerosis. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

MSDisseminated Sclerosismuscular sclerosis

Related ICD-10 Code Ranges

Complete code families applicable to Multiple Sclerosis

G35Primary Range

Multiple sclerosis

This is the primary code for diagnosing multiple sclerosis, covering all types and stages of the disease.

Other demyelinating diseases of central nervous system

These codes are used for conditions that may be considered in the differential diagnosis of multiple sclerosis.

Key Information: ICD-10 code for multiple sclerosis

Essential facts and insights about Multiple Sclerosis

The ICD-10 code for multiple sclerosis is G35, encompassing all types and stages of the disease.

Primary ICD-10-CM Code for multiple sclerosis

Multiple sclerosis
Billable Code

Decision Criteria

clinical Criteria

  • Presence of clinical relapses and MRI findings consistent with MS.

documentation Criteria

  • Detailed documentation of subtype and disease progression.

Applicable To

  • Relapsing-remitting multiple sclerosis
  • Primary progressive multiple sclerosis
  • Secondary progressive multiple sclerosis

Excludes

  • Neuromyelitis optica (G36.0)
  • Acute disseminated encephalitis (G04.0)

Clinical Validation Requirements

  • MRI showing lesions disseminated in time and space
  • Positive CSF oligoclonal bands
  • Clinical history of relapses and remissions

Code-Specific Risks

  • Risk of under-documenting subtype and progression status
  • Potential for incorrect coding if differential diagnosis is not considered

Coding Notes

  • Ensure to document the subtype and any manifestations clearly to support the use of G35.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Optic neuritis

H46.13
Use when optic neuritis is a manifestation of multiple sclerosis.

Neuropathic pain

G58.0
Use to document neuropathic pain associated with multiple sclerosis.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Neuromyelitis optica

G36.9
Requires anti-AQP4 antibody positivity and distinct clinical presentation.

Acute transverse myelitis

G37.3
Characterized by acute onset and often monophasic course.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Multiple Sclerosis to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code G35.

Impact

Clinical: May lead to inappropriate treatment decisions., Regulatory: Increases risk of audit failure., Financial: Potential loss of reimbursement for lack of supporting documentation.

Mitigation Strategy

Ensure MRI results are included in the patient's record., Regularly update documentation with new imaging findings.

Impact

Reimbursement: May lead to lower reimbursement rates., Compliance: Increases risk of audit due to lack of specificity., Data Quality: Reduces the quality of clinical data for research and treatment planning.

Mitigation Strategy

Always document and code the specific subtype of MS if known.

Impact

Using unspecified codes when specific subtypes are documented.

Mitigation Strategy

Always document and code the specific subtype of MS.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Multiple Sclerosis, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Multiple Sclerosis

Use these documentation templates to ensure complete and accurate documentation for Multiple Sclerosis. These templates include all required elements for proper coding and billing.

Relapsing-remitting multiple sclerosis with active progression

Specialty: Neurology

Required Elements

  • Disease activity status
  • MRI findings
  • DMT compliance
  • Complications

Example Documentation

**MS Status:** - [X] Clinical relapse (onset: 03/15/2025) - MRI: New C3 spinal cord lesion - DMT: Ocrelizumab, last infusion 02/01/2025 - Complications: Spasticity, Modified Ashworth 2+ bilateral LE

Examples: Poor vs. Good Documentation

Poor Documentation Example
MS flare-up
Good Documentation Example
Acute relapse of RRMS with new C3 spinal cord lesion on contrast-enhanced MRI, EDSS increased from 3.0 to 4.5
Explanation
The good example provides specific details on the relapse, MRI findings, and EDSS score, which are crucial for accurate coding and treatment planning.

Need help with ICD-10 coding for Multiple Sclerosis? Ask your questions below.

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