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ICD-10 Coding for Nephrotic Syndrome(N04.2, N04.21)

Complete ICD-10-CM coding and documentation guide for Nephrotic Syndrome. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

NephrosisNephrotic Range Proteinuria

Related ICD-10 Code Ranges

Complete code families applicable to Nephrotic Syndrome

N04-N08Primary Range

Nephrotic syndrome and related conditions

This range includes all codes related to nephrotic syndrome, covering various morphologies and etiologies.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
N04.2Nephrotic syndrome with diffuse membranous glomerulonephritisUse when biopsy confirms diffuse membranous glomerulonephritis with nephrotic syndrome.
  • Biopsy confirmation of membranous glomerulonephritis
  • Nephrotic-range proteinuria (≥3.5 g/day)
N04.21Nephrotic syndrome with primary membranous nephropathyUse when primary membranous nephropathy is confirmed by biopsy.
  • Biopsy confirmation of primary membranous nephropathy
  • Nephrotic-range proteinuria (≥3.5 g/day)

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for nephrotic syndrome

Essential facts and insights about Nephrotic Syndrome

The ICD-10 code for nephrotic syndrome with diffuse membranous glomerulonephritis is N04.2, requiring biopsy confirmation.

Primary ICD-10-CM Codes for nephrotic syndrome

Nephrotic syndrome with diffuse membranous glomerulonephritis
Non-billable Code

Decision Criteria

clinical Criteria

  • Biopsy confirms diffuse membranous glomerulonephritis.

documentation Criteria

  • Document nephrotic-range proteinuria and biopsy results.

Applicable To

  • Primary membranous nephropathy

Excludes

  • Secondary membranous nephropathy (N04.22)

Clinical Validation Requirements

  • Biopsy confirmation of membranous glomerulonephritis
  • Nephrotic-range proteinuria (≥3.5 g/day)

Code-Specific Risks

  • Misclassification if biopsy results are not documented.

Coding Notes

  • Ensure biopsy results are clearly documented to support the use of this code.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Hyperlipidemia

E78.5
Use when hyperlipidemia is present in nephrotic syndrome cases.

Edema, unspecified

R60.9
Use when edema is present in nephrotic syndrome cases.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Nephrotic syndrome with focal segmental glomerulosclerosis

N04.1
Biopsy shows segmental scarring, not diffuse membranous changes.

Nephrotic syndrome with secondary membranous nephropathy

N04.22
Secondary to another condition like hepatitis B or lupus.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Nephrotic Syndrome to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code N04.2.

Impact

Clinical: Inaccurate diagnosis and treatment planning., Regulatory: Non-compliance with coding standards., Financial: Potential reimbursement issues due to incorrect DRG assignment.

Mitigation Strategy

Ensure biopsy results are documented before coding., Train staff on the importance of complete documentation.

Impact

Reimbursement: Incorrect DRG assignment may affect reimbursement., Compliance: Non-compliance with coding guidelines., Data Quality: Inaccurate clinical data affecting patient records.

Mitigation Strategy

Verify biopsy results and document primary or secondary etiology clearly.

Impact

Lack of biopsy documentation can lead to incorrect coding.

Mitigation Strategy

Implement a checklist to ensure biopsy results are included in patient records.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Nephrotic Syndrome, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Nephrotic Syndrome

Use these documentation templates to ensure complete and accurate documentation for Nephrotic Syndrome. These templates include all required elements for proper coding and billing.

Nephrotic syndrome with primary membranous nephropathy

Specialty: Nephrology

Required Elements

  • Biopsy results
  • Proteinuria levels
  • Serum albumin levels

Example Documentation

Assessment: Primary membranous nephropathy confirmed by biopsy. Proteinuria: 4.2 g/24 hr. Plan: Start rituximab.

Examples: Poor vs. Good Documentation

Poor Documentation Example
Nephrotic syndrome present.
Good Documentation Example
Primary membranous nephropathy confirmed by biopsy with proteinuria 4.2 g/24 hr.
Explanation
The good example provides specific biopsy results and proteinuria levels, supporting accurate coding.

Need help with ICD-10 coding for Nephrotic Syndrome? Ask your questions below.

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