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ICD-10 Coding for Myeloproliferative Neoplasms(D45.0, D47.3)

Complete ICD-10-CM coding and documentation guide for Myeloproliferative Neoplasms. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

MPNChronic Myeloproliferative Disorders

Related ICD-10 Code Ranges

Complete code families applicable to Myeloproliferative Neoplasms

D45-D47Primary Range

Myeloproliferative diseases

This range includes codes for various types of myeloproliferative neoplasms, which are the primary focus of this documentation.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
D45.0Polycythemia VeraUse when Polycythemia Vera is confirmed with JAK2 mutation and elevated hemoglobin/hematocrit.
  • JAK2 V617F mutation
  • Elevated hemoglobin and hematocrit
D47.3Essential ThrombocythemiaUse when Essential Thrombocythemia is confirmed with CALR/MPL mutation and elevated platelet count.
  • CALR/MPL mutation
  • Platelet count >450k/µL

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for Polycythemia Vera

Essential facts and insights about Myeloproliferative Neoplasms

The ICD-10 code for Polycythemia Vera is D45.0, used when confirmed by JAK2 mutation and elevated hemoglobin levels.

Primary ICD-10-CM Codes for probable number

Polycythemia Vera
Non-billable Code

Decision Criteria

clinical Criteria

  • Presence of JAK2 mutation and elevated hemoglobin

Applicable To

  • JAK2 mutation positive Polycythemia Vera

Excludes

  • Secondary polycythemia (D75.1)

Clinical Validation Requirements

  • JAK2 V617F mutation
  • Elevated hemoglobin and hematocrit

Code-Specific Risks

  • Misclassification if JAK2 mutation is not confirmed

Coding Notes

  • Ensure JAK2 mutation is documented for accurate coding.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Splenomegaly

R16.1
Use to document splenomegaly as a manifestation of Polycythemia Vera.

Thrombocytosis

R71.0
Use to document thrombocytosis as a manifestation of Essential Thrombocythemia.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Secondary polycythemia

D75.1
Secondary polycythemia is due to external factors such as hypoxia, not a primary bone marrow disorder.

Reactive thrombocytosis

D75.81
Reactive thrombocytosis is due to another condition such as infection or inflammation.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Myeloproliferative Neoplasms to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code D45.0.

Impact

Clinical: May lead to misdiagnosis., Regulatory: Non-compliance with coding standards., Financial: Potential claim denials.

Mitigation Strategy

Ensure all genetic test results are documented.

Impact

Reimbursement: May lead to denied claims or reduced reimbursement., Compliance: Non-compliance with coding guidelines., Data Quality: Decreases accuracy of clinical data.

Mitigation Strategy

Always use specific codes like D45.0 or D47.3 when mutations are confirmed.

Impact

Lack of documentation for genetic testing results.

Mitigation Strategy

Ensure all test results are included in the patient's record.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Myeloproliferative Neoplasms, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Myeloproliferative Neoplasms

Use these documentation templates to ensure complete and accurate documentation for Myeloproliferative Neoplasms. These templates include all required elements for proper coding and billing.

Diagnosis of Polycythemia Vera

Specialty: Hematology

Required Elements

  • JAK2 mutation status
  • Hemoglobin and hematocrit levels
  • Presence of splenomegaly

Examples: Poor vs. Good Documentation

Poor Documentation Example
Patient has high red blood cell count.
Good Documentation Example
Patient diagnosed with Polycythemia Vera, confirmed by JAK2 V617F mutation and elevated hemoglobin levels.
Explanation
The good example includes specific mutation and lab results, supporting the diagnosis.

Need help with ICD-10 coding for Myeloproliferative Neoplasms? Ask your questions below.

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