ICD-10 Coding for Infusion of Immunoglobulins(D80.0, G61.81, D69.3)
Complete ICD-10-CM coding and documentation guide for Infusion of Immunoglobulins. Includes clinical validation requirements, documentation requirements, and coding pitfalls.
Also known as:
Related ICD-10 Code Ranges
Complete code families applicable to Infusion of Immunoglobulins
D80-D89Primary Range
Disorders of the immune system
This range includes primary immunodeficiencies and conditions treated with immunoglobulin infusions.
Polyneuropathies and other disorders of the peripheral nervous system
Includes conditions like CIDP that may require immunoglobulin infusion.
Purpura and other hemorrhagic conditions
Includes chronic ITP, a condition treated with immunoglobulin infusions.
Code Comparison: When to Use Each Code
Compare key differences between these codes to ensure accurate selection
| Code | Description | When to Use | Key Documentation |
|---|---|---|---|
| D80.0 | Hereditary hypogammaglobulinemia | Use for confirmed hereditary hypogammaglobulinemia with documented low IgG levels. |
|
| G61.81 | Chronic inflammatory demyelinating polyneuritis | Use for CIDP with documented clinical and electrodiagnostic evidence. |
|
| D69.3 | Immune thrombocytopenic purpura | Use for chronic ITP with documented low platelet count and treatment resistance. |
|
Clinical Decision Support
Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.
Key Information: ICD-10 code for hereditary hypogammaglobulinemia
Essential facts and insights about Infusion of Immunoglobulins
Primary ICD-10-CM Codes for procedure infusion of immunoglobulins
Decision Criteria
clinical Criteria
- Presence of genetic confirmation and low IgG levels
Applicable To
- Primary immunodeficiency
Excludes
- Secondary immunodeficiency (D84.9)
Clinical Validation Requirements
- Serum IgG < 400 mg/dL
- Recurrent sinopulmonary infections
Code-Specific Risks
- Misclassification with secondary immunodeficiency
Coding Notes
- Ensure genetic confirmation for hereditary classification.
G61.81 - Chronic inflammatory demyelinating polyneuritis
Use for CIDP with documented clinical and electrodiagnostic evidence.
Applicable To
- CIDP
Excludes
- Acute inflammatory demyelinating polyneuritis (G61.0)
Clinical Validation Requirements
- Progressive symmetric weakness
- Elevated CSF protein
- Nerve conduction studies showing demyelination
Coding Notes
Ensure differentiation from acute neuropathies.
D69.3 - Immune thrombocytopenic purpura
Use for chronic ITP with documented low platelet count and treatment resistance.
Applicable To
- Chronic ITP
Excludes
- Drug-induced thrombocytopenia (D69.5)
Clinical Validation Requirements
- Platelet count < 30,000/μL
- Unresponsive to corticosteroids
Coding Notes
Ensure exclusion of secondary causes.
Ancillary Codes
Additional codes that should be used in conjunction with the main diagnosis codes when applicable.
Bone marrow transplant status
Z94.81Differential Codes
Alternative codes to consider when ruling out similar conditions to the primary diagnosis.
Documentation & Coding Risks
Avoid these common documentation and coding issues when documenting Infusion of Immunoglobulins to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code D80.0.
Impact
Clinical: Inadequate treatment justification, Regulatory: Non-compliance with documentation standards, Financial: Potential claim denials
Mitigation Strategy
Use specific ICD-10 codes, Include detailed clinical evidence
Impact
Reimbursement: Denial of claims, Compliance: Non-compliance with coding guidelines, Data Quality: Inaccurate clinical data representation
Mitigation Strategy
Always sequence the underlying condition before the procedure code.
Impact
Reimbursement: Potential claim denials, Compliance: Incorrect billing, Data Quality: Misleading treatment records
Mitigation Strategy
Verify the specific IG product and administration route before coding.
Impact
Using incorrect J codes for different immunoglobulin products.
Mitigation Strategy
Verify product and administration route before coding.
Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.
Frequently Asked Questions
Common questions about ICD-10 coding for Infusion of Immunoglobulins, with expert answers to help guide accurate code selection and documentation.
Documentation Templates for Infusion of Immunoglobulins
Use these documentation templates to ensure complete and accurate documentation for Infusion of Immunoglobulins. These templates include all required elements for proper coding and billing.
CIDP requiring IVIG
Specialty: NeurologyRequired Elements
- Diagnosis
- Indication for IVIG
- Infusion details
- Monitoring plan
Example Documentation
Examples: Poor vs. Good Documentation
Poor Documentation Example
Good Documentation Example
Explanation
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