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ICD-10 Coding for Tetrahydrocortisol Use(E27.40, R94.6)

Complete ICD-10-CM coding and documentation guide for Tetrahydrocortisol Use. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

THF UseCortisol Metabolite Testing

Related ICD-10 Code Ranges

Complete code families applicable to Tetrahydrocortisol Use

E27-E29Primary Range

Disorders of adrenal glands

This range includes primary adrenal disorders that may necessitate tetrahydrocortisol testing.

Abnormal results of function studies

This range includes codes for abnormal cortisol levels, which may be identified through tetrahydrocortisol testing.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
E27.40Adrenocortical insufficiency, unspecifiedUse when adrenal insufficiency is suspected based on clinical symptoms and lab findings.
  • Urinary 5α-THF/THF ratio >1.5
  • Elevated serum ACTH levels
R94.6Abnormal cortisol levelsUse when lab results indicate abnormal cortisol levels without a confirmed adrenal disorder.
  • Documented abnormal cortisol metabolite levels

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for tetrahydrocortisol use

Essential facts and insights about Tetrahydrocortisol Use

The ICD-10 code for tetrahydrocortisol use is typically associated with adrenal disorders like E27.40 for adrenocortical insufficiency.

Primary ICD-10-CM Codes for tetrahydrocortisol use

Adrenocortical insufficiency, unspecified
Billable Code

Decision Criteria

clinical Criteria

  • Presence of symptoms like fatigue, hypotension, and electrolyte imbalance.

documentation Criteria

  • Documented abnormal urinary THF/5α-THF ratio.

Applicable To

  • Primary adrenal insufficiency

Excludes

  • Congenital adrenal hyperplasia (E25.0)

Clinical Validation Requirements

  • Urinary 5α-THF/THF ratio >1.5
  • Elevated serum ACTH levels

Code-Specific Risks

  • Misclassification if not supported by lab results

Coding Notes

  • Ensure documentation includes specific metabolite ratios and test methods.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

THF/5α-THF ratio

LOINC 82908-5
Use to quantify cortisol metabolite ratios for diagnostic validation.

Pregnanediol/THE+THF+5α-THF ratio

LOINC 82894-7
Use to support findings of abnormal cortisol metabolism.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Adrenogenital disorder, unspecified

E25.9
Use when genetic testing confirms enzyme deficiency affecting cortisol metabolism.

Adrenocortical insufficiency, unspecified

E27.40
Use E27.40 when clinical symptoms and lab results confirm adrenal insufficiency.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Tetrahydrocortisol Use to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code E27.40.

Impact

Clinical: May lead to misdiagnosis., Regulatory: Non-compliance with documentation standards., Financial: Potential claim denials.

Mitigation Strategy

Use specific lab values and ratios., Ensure documentation includes test methods.

Impact

Reimbursement: May lead to claim denials due to lack of specificity., Compliance: Non-compliance with coding guidelines for specificity., Data Quality: Reduces accuracy of clinical data.

Mitigation Strategy

Add E27.40 and LOINC 82908-5 when ratios confirm adrenal dysfunction.

Impact

Risk of audits due to non-specific coding of adrenal disorders.

Mitigation Strategy

Ensure documentation supports specific adrenal disorder codes.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Tetrahydrocortisol Use, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Tetrahydrocortisol Use

Use these documentation templates to ensure complete and accurate documentation for Tetrahydrocortisol Use. These templates include all required elements for proper coding and billing.

Adrenal Insufficiency Diagnosis

Specialty: Endocrinology

Required Elements

  • Clinical symptoms
  • Lab results with specific ratios
  • Treatment plan

Example Documentation

Assessment: Suspected adrenal insufficiency. Findings: Elevated urinary THF/5α-THF ratio (3.1; ref: 0.8-1.5) via mass spectrometry. Plan: Genetic testing for HSD11B2 mutation.

Examples: Poor vs. Good Documentation

Poor Documentation Example
Abnormal cortisol metabolites noted.
Good Documentation Example
Urinary 5α-THF/THF ratio of 2.5 via LC-MS/MS confirms impaired 11β-HSD2 activity.
Explanation
The good example provides specific lab results and testing methods, supporting the diagnosis.

Need help with ICD-10 coding for Tetrahydrocortisol Use? Ask your questions below.

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