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ICD-10 Coding for Thalassemia Anemia(D56.0, D56.1)

Complete ICD-10-CM coding and documentation guide for Thalassemia Anemia. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

Cooley's AnemiaMediterranean AnemiaHemoglobinopathy

Related ICD-10 Code Ranges

Complete code families applicable to Thalassemia Anemia

D56-D56.9Primary Range

Thalassemia

This range covers all types of thalassemia, including alpha, beta, and other variants.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
D56.0Alpha thalassemiaUse for confirmed cases of alpha thalassemia, particularly when HbH disease is present.
  • Hemoglobin electrophoresis showing HbH
  • Genetic testing confirming α-globin gene deletion
D56.1Beta thalassemiaUse for confirmed cases of beta thalassemia, especially when transfusion dependence is documented.
  • HPLC showing elevated HbA2
  • Genetic testing confirming β-globin mutation

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for beta thalassemia

Essential facts and insights about Thalassemia Anemia

The ICD-10 code for beta thalassemia is D56.1, used for confirmed cases with elevated HbA2 levels.

Primary ICD-10-CM Codes for thalassemia anemia

Alpha thalassemia
Billable Code

Decision Criteria

clinical Criteria

  • Presence of HbH on electrophoresis

Applicable To

  • Hemoglobin H disease
  • Alpha thalassemia major

Excludes

  • Sickle-cell thalassemia (D57.4)

Clinical Validation Requirements

  • Hemoglobin electrophoresis showing HbH
  • Genetic testing confirming α-globin gene deletion

Code-Specific Risks

  • Misclassification if genetic testing is not performed

Coding Notes

  • Ensure genetic testing results are documented to support the use of this code.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Long-term (current) use of other medications

Z79.2
Use when patient is on iron chelation therapy.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Beta thalassemia

D56.1
Use when beta thalassemia is confirmed by high HbA2 levels on HPLC.

Alpha thalassemia

D56.0
Use when alpha thalassemia is confirmed by genetic testing.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Thalassemia Anemia to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code D56.0.

Impact

Clinical: May lead to inappropriate treatment., Regulatory: Non-compliance with documentation standards., Financial: Potential for denied claims.

Mitigation Strategy

Ensure genetic testing is ordered and results are documented., Use templates to capture all necessary information.

Impact

Reimbursement: May result in lower reimbursement rates., Compliance: Non-compliance with coding guidelines., Data Quality: Decreases accuracy of patient records.

Mitigation Strategy

Query provider for specific type of thalassemia and use the appropriate code.

Impact

High risk of audit if unspecified codes are used when specific types are known.

Mitigation Strategy

Always query for specific type and document genetic testing results.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Thalassemia Anemia, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Thalassemia Anemia

Use these documentation templates to ensure complete and accurate documentation for Thalassemia Anemia. These templates include all required elements for proper coding and billing.

Thalassemia Management

Specialty: Hematology

Required Elements

  • Diagnosis confirmation
  • Genetic testing results
  • Transfusion history
  • Iron studies

Example Documentation

Patient with confirmed beta thalassemia major, HPLC showing HbA2 4.5%, requires monthly transfusions.

Examples: Poor vs. Good Documentation

Poor Documentation Example
Anemia due to thalassemia.
Good Documentation Example
Beta thalassemia major confirmed by HPLC, transfusion-dependent.
Explanation
The good example specifies the type and severity of thalassemia.

Need help with ICD-10 coding for Thalassemia Anemia? Ask your questions below.

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