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ICD-10 Coding for Transaminitis Secondary to Rosuvastatin(T46.6X5A, K71.9, R74.01)

Complete ICD-10-CM coding and documentation guide for Transaminitis Secondary to Rosuvastatin. Includes clinical validation requirements, documentation requirements, and coding pitfalls.

Also known as:

Statin-Induced Liver InjuryRosuvastatin-Induced Hepatotoxicity

Related ICD-10 Code Ranges

Complete code families applicable to Transaminitis Secondary to Rosuvastatin

T36-T50Primary Range

Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances

This range includes codes for adverse effects of drugs, including statins like rosuvastatin.

Diseases of liver

This range includes codes for liver diseases, including toxic liver disease and elevated liver enzymes.

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

CodeDescriptionWhen to UseKey Documentation
T46.6X5AAdverse effect of antihyperlipidemic and antiarteriosclerotic drugs, initial encounterUse when there is a documented adverse effect of rosuvastatin causing liver enzyme elevation.
  • Documented adverse reaction to rosuvastatin
  • Temporal relationship between drug administration and symptom onset
K71.9Toxic liver disease, unspecifiedUse when there is confirmed drug-induced liver injury without specific etiology.
  • Exclusion of viral and autoimmune hepatitis
  • Liver biopsy or imaging confirming hepatocellular injury
R74.01Elevation of levels of liver transaminases and lactic acid dehydrogenase [LDH]Use when there is an elevation of liver enzymes without a specific diagnosis of liver disease.
  • Documented lab results showing elevated ALT/AST levels

Clinical Decision Support

Always review the patient's clinical documentation thoroughly. When in doubt, choose the more specific code and ensure documentation supports it.

Key Information: ICD-10 code for transaminitis due to rosuvastatin

Essential facts and insights about Transaminitis Secondary to Rosuvastatin

The ICD-10 code for transaminitis due to rosuvastatin is T46.6X5A, indicating an adverse effect of antihyperlipidemic drugs, combined with R74.01 for elevated liver enzymes.

Primary ICD-10-CM Codes for transaminitis secondary to rosuvastatin

Adverse effect of antihyperlipidemic and antiarteriosclerotic drugs, initial encounter
Billable Code

Decision Criteria

clinical Criteria

  • Presence of elevated liver enzymes temporally related to rosuvastatin use.

documentation Criteria

  • Explicit mention of rosuvastatin as the cause of liver enzyme elevation.

Applicable To

  • Adverse effect of rosuvastatin

Excludes

  • Poisoning by antihyperlipidemic drugs (T46.6X1-)

Clinical Validation Requirements

  • Documented adverse reaction to rosuvastatin
  • Temporal relationship between drug administration and symptom onset

Code-Specific Risks

  • Failure to document the drug as the cause can lead to incorrect coding.

Coding Notes

  • Always pair T46.6X5A with a code for the specific liver condition caused by the drug.

Ancillary Codes

Additional codes that should be used in conjunction with the main diagnosis codes when applicable.

Pure hypercholesterolemia

E78.00
Use to indicate the underlying condition for which rosuvastatin was prescribed.

Long term (current) use of insulin

Z79.4
Use to document long-term use of statins.

Differential Codes

Alternative codes to consider when ruling out similar conditions to the primary diagnosis.

Poisoning by antihyperlipidemic and antiarteriosclerotic drugs, accidental (unintentional), initial encounter

T46.6X1A
Use for accidental overdose rather than adverse effect.

Inflammatory liver disease, unspecified

K75.9
Use when the cause of liver inflammation is not identified as drug-induced.

Toxic liver disease, unspecified

K71.9
Use K71.9 when there is a confirmed diagnosis of drug-induced liver injury.

Documentation & Coding Risks

Avoid these common documentation and coding issues when documenting Transaminitis Secondary to Rosuvastatin to ensure proper reimbursement, maintain compliance, and reduce audit risk. These guidelines are particularly important when using ICD-10 code T46.6X5A.

Impact

Clinical: May lead to misdiagnosis and inappropriate treatment., Regulatory: Non-compliance with coding standards., Financial: Potential for denied claims or reduced reimbursement.

Mitigation Strategy

Ensure documentation explicitly states drug as cause., Use templates to guide documentation.

Impact

Reimbursement: May lead to lower reimbursement due to incomplete coding., Compliance: Non-compliance with ICD-10 coding guidelines., Data Quality: Inaccurate representation of the patient's condition.

Mitigation Strategy

Always pair R74.01 with T46.6X5A for adverse drug reactions.

Impact

Reimbursement: Incorrect coding may affect DRG assignment., Compliance: Misrepresentation of the patient's condition., Data Quality: Inaccurate clinical data for research and analysis.

Mitigation Strategy

Use T46.6X5A for adverse effects, not Z91.14 for intolerance.

Impact

Failure to use both adverse effect and liver condition codes.

Mitigation Strategy

Implement coding audits and education on proper code combinations.

Documentation errors, coding pitfalls, and audit risks are interconnected aspects of medical coding and billing. Addressing all three areas helps ensure accurate coding, optimal reimbursement, and regulatory compliance.

Frequently Asked Questions

Common questions about ICD-10 coding for Transaminitis Secondary to Rosuvastatin, with expert answers to help guide accurate code selection and documentation.

Documentation Templates for Transaminitis Secondary to Rosuvastatin

Use these documentation templates to ensure complete and accurate documentation for Transaminitis Secondary to Rosuvastatin. These templates include all required elements for proper coding and billing.

Patient with elevated liver enzymes due to rosuvastatin

Specialty: Gastroenterology

Required Elements

  • Patient history of rosuvastatin use
  • Lab results showing elevated ALT/AST
  • Exclusion of other liver disease causes
  • Plan for discontinuation of rosuvastatin

Example Documentation

47M with hypercholesterolemia on rosuvastatin 20 mg presents with fatigue. Labs: ALT 220 U/L, AST 180 U/L. Diagnosis: Transaminitis secondary to rosuvastatin. Plan: Discontinue statin, monitor LFTs.

Examples: Poor vs. Good Documentation

Poor Documentation Example
Elevated LFTs noted.
Good Documentation Example
ALT 220 U/L (5x ULN), AST 180 U/L (4x ULN) 8 weeks after rosuvastatin 20 mg initiation.
Explanation
The good example provides specific lab values and links them to drug use.

Need help with ICD-10 coding for Transaminitis Secondary to Rosuvastatin? Ask your questions below.

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